STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mboo_0727KEGG: mhu:Mhun_0095 succinyl-CoA synthetase, beta subunit; TIGRFAM: succinyl-CoA synthetase, beta subunit; PFAM: ATP-citrate lyase/succinyl-CoA ligase; ATP-grasp domain protein. (361 aa)    
Predicted Functional Partners:
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 0.999
Mboo_0086
PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mhu:Mhun_3053 succinate dehydrogenase.
 0.995
Mboo_0728
PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: mhu:Mhun_0094 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate.
 
 
 0.989
Mboo_0729
PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: mhu:Mhun_0093 thiamine pyrophosphate enzyme-like TPP-binding.
  
 
 0.988
Mboo_0730
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: mhu:Mhun_0092 pyruvate flavodoxin/ferredoxin oxidoreductase-like.
  
 
 0.988
Mboo_0731
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: mhu:Mhun_0091 4Fe-4S ferredoxin, iron-sulfur binding.
    
  0.983
Mboo_0085
TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: ferredoxin; 4Fe-4S ferredoxin, iron-sulfur binding domain protein; protein of unknown function DUF224, cysteine-rich region domain protein; KEGG: mhu:Mhun_3052 succinate dehydrogenase and fumarate reductase iron-sulfur protein.
 
 
 0.958
Mboo_2091
PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: mhu:Mhun_2992 pyruvate flavodoxin/ferredoxin oxidoreductase-like.
  
 
 0.930
Mboo_2090
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: mhu:Mhun_2993 thiamine pyrophosphate enzyme-like TPP-binding.
  
 
 0.929
Mboo_0156
PFAM: Thiolase; KEGG: mhu:Mhun_0150 thiolase.
  
 
 0.902
Your Current Organism:
Methanoregula boonei
NCBI taxonomy Id: 456442
Other names: Candidatus Methanoregula boonei 6A8, M. boonei 6A8, Methanoregula boonei 6A8, Methanoregula boonei str. 6A8, Methanoregula boonei strain 6A8, methanogenic archaeon 6A8
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