STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mboo_0778PFAM: Carboxylesterase, type B; KEGG: sus:Acid_2915 carboxylesterase, type B. (508 aa)    
Predicted Functional Partners:
Mboo_0949
PFAM: Cupin 2, conserved barrel domain protein; KEGG: mba:Mbar_A0776 hypothetical protein.
 
  
 0.848
Mboo_0029
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: mhu:Mhun_1746 4Fe-4S ferredoxin, iron-sulfur binding.
  
 
 0.802
Mboo_1123
PFAM: NADH-ubiquinone oxidoreductase, chain 49kDa; NADH dehydrogenase (ubiquinone), 30 kDa subunit; KEGG: mma:MM1063 formate hydrogenlyase subunit 5 precursor.
   
   0.714
Mboo_0100
PFAM: AMP-dependent synthetase and ligase; KEGG: mhu:Mhun_2450 AMP-dependent synthetase and ligase.
  
 
 0.627
Mboo_0770
PFAM: AMP-dependent synthetase and ligase; KEGG: mhu:Mhun_1627 AMP-dependent synthetase and ligase.
  
 
 0.627
Mboo_1742
PFAM: AMP-dependent synthetase and ligase; KEGG: mhu:Mhun_3111 AMP-dependent synthetase and ligase.
  
 
 0.627
Mboo_0777
PFAM: alpha/beta hydrolase fold; KEGG: mac:MA2691 lipolytic enzyme.
 
  
 0.614
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.562
dnaJ-2
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.562
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
  
   0.542
Your Current Organism:
Methanoregula boonei
NCBI taxonomy Id: 456442
Other names: Candidatus Methanoregula boonei 6A8, M. boonei 6A8, Methanoregula boonei 6A8, Methanoregula boonei str. 6A8, Methanoregula boonei strain 6A8, methanogenic archaeon 6A8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.