STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mboo_0886PFAM: NUDIX hydrolase; KEGG: mac:MA1439 NAD+ pyrophosphatase. (291 aa)    
Predicted Functional Partners:
Mboo_1086
PFAM: 5'-Nucleotidase domain protein; KEGG: mhu:Mhun_2724 5'-nucleotidase-like.
 
  
  0.940
Mboo_0766
PFAM: Quinolinate phosphoribosyl transferase; KEGG: afu:AF0821 nicotinate phosphoribosyltransferase.
    
 0.938
surE
Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
 
 
  0.934
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
  
 
 0.919
Mboo_0499
Nicotinate-nucleotide pyrophosphorylase; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family.
    
 0.914
nadK
NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.912
Mboo_1731
KEGG: mhu:Mhun_2915 nicotinamide-nucleotide adenylyltransferase; TIGRFAM: cytidyltransferase-related domain; nicotinamide-nucleotide adenylyltransferase; PFAM: cytidylyltransferase.
     
 0.903
Mboo_1315
NAD(P)(+) transhydrogenase (AB-specific); PFAM: alanine dehydrogenase/PNT domain protein; KEGG: aeh:Mlg_2771 NAD(P)(+) transhydrogenase (AB-specific).
     
  0.900
Mboo_1316
KEGG: aeh:Mlg_2770 pyridine nucleotide transhydrogenase subunit alpha.
     
  0.900
Mboo_1317
PFAM: NAD(P) transhydrogenase, beta subunit; KEGG: ttj:TTHA0208 nicotinamide nucleotide transhydrogenase, beta subunit.
     
  0.900
Your Current Organism:
Methanoregula boonei
NCBI taxonomy Id: 456442
Other names: Candidatus Methanoregula boonei 6A8, M. boonei 6A8, Methanoregula boonei 6A8, Methanoregula boonei str. 6A8, Methanoregula boonei strain 6A8, methanogenic archaeon 6A8
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