STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mboo_1031PFAM: N-6 DNA methylase; KEGG: mma:MM2704 type I restriction-modification system specificity subunit. (477 aa)    
Predicted Functional Partners:
Mboo_1032
PFAM: restriction modification system DNA specificity domain; KEGG: mma:MM2703 type I restriction-modification system specificity subunit.
 
 0.998
Mboo_1030
PFAM: helicase domain protein; type III restriction enzyme, res subunit; protein of unknown function DUF450; SMART: DEAD-like helicases-like; KEGG: mma:MM2705 type I restriction-modification system restriction subunit.
 
 
 0.989
uvrB
Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
   
 
 0.744
Mboo_1033
Hypothetical protein.
       0.737
Mboo_1330
PFAM: protein of unknown function DUF814; KEGG: mhu:Mhun_0437 protein of unknown function DUF814.
  
  
 0.571
Mboo_1029
Hypothetical protein.
       0.552
Mboo_0830
Putative transcriptional regulator; PFAM: AAA-4 family protein.
  
    0.474
Your Current Organism:
Methanoregula boonei
NCBI taxonomy Id: 456442
Other names: Candidatus Methanoregula boonei 6A8, M. boonei 6A8, Methanoregula boonei 6A8, Methanoregula boonei str. 6A8, Methanoregula boonei strain 6A8, methanogenic archaeon 6A8
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.