STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
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Experiments
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[Homology]
Score
Mboo_1333Hypothetical protein; KEGG: bth:BT3678 two-component system sensor histidine kinase/response regulator, hybrid ('one-component system'). (406 aa)    
Predicted Functional Partners:
cheD
CheD, stimulates methylation of MCP proteins; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
       0.779
Mboo_1335
CheC, inhibitor of MCP methylation; PFAM: CheC domain protein; KEGG: mhu:Mhun_0110 CheA signal transduction histidine kinases.
       0.545
Mboo_1336
CheA signal transduction histidine kinase; PFAM: CheW domain protein; ATP-binding region, ATPase domain protein domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein; P2 response regulator binding domain protein; KEGG: mhu:Mhun_0110 CheA signal transduction histidine kinases.
       0.543
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
       0.543
Mboo_1338
PFAM: response regulator receiver; KEGG: mhu:Mhun_0108 response regulator receiver domain protein (CheY-like).
       0.539
Mboo_2451
PFAM: glycosyl transferase, family 39; KEGG: mbu:Mbur_1617 hypothetical protein.
  
     0.450
Mboo_1339
KEGG: mhu:Mhun_0107 hypothetical protein.
       0.424
Mboo_0313
PFAM: PKD domain containing protein; KEGG: mac:MA4589 cell surface protein.
  
     0.418
Your Current Organism:
Methanoregula boonei
NCBI taxonomy Id: 456442
Other names: Candidatus Methanoregula boonei 6A8, M. boonei 6A8, Methanoregula boonei 6A8, Methanoregula boonei str. 6A8, Methanoregula boonei strain 6A8, methanogenic archaeon 6A8
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