STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mboo_1413TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: mhu:Mhun_0935 hydrogenase expression/formation protein HypE. (331 aa)    
Predicted Functional Partners:
Mboo_1301
TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; KEGG: mhu:Mhun_0502 hydrogenase expression/formation protein HypD.
 
 0.997
Mboo_1411
TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: mhu:Mhun_1499 hydrogenase assembly chaperone HypC/HupF.
 
 
 0.995
Mboo_2246
TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: acylphosphatase; SUA5/yciO/yrdC, N-terminal domain; zinc finger, HypF domain protein; KEGG: mhu:Mhun_2500 (NiFe) hydrogenase maturation protein HypF.
 
 
 0.990
hypA
Hydrogenase expression/synthesis, HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
  
  
 0.919
Mboo_1123
PFAM: NADH-ubiquinone oxidoreductase, chain 49kDa; NADH dehydrogenase (ubiquinone), 30 kDa subunit; KEGG: mma:MM1063 formate hydrogenlyase subunit 5 precursor.
   
 
 0.876
Mboo_2308
TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein, P47K; KEGG: mhu:Mhun_2484 hydrogenase accessory protein HypB.
 
  
 0.785
Mboo_2023
PFAM: nickel-dependent hydrogenase, large subunit; KEGG: mac:MA0975 coenzyme F420 hydrogenase, subunit alpha; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
   
 0.779
Mboo_0479
Coenzyme F420 hydrogenase; PFAM: nickel-dependent hydrogenase, large subunit; KEGG: mma:MM3045 coenzyme F420 hydrogenase, alpha subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
   
 0.768
Mboo_0478
TIGRFAM: hydrogenase maturation protease; PFAM: peptidase M52, hydrogen uptake protein; KEGG: mhu:Mhun_2331 peptidase M52, hydrogenase maturation peptidase.
 
   
 0.695
Mboo_0477
Coenzyme F420 hydrogenase; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; NADH ubiquinone oxidoreductase, 20 kDa subunit; KEGG: mhu:Mhun_2330 coenzyme F420 hydrogenase.
 
   
 0.561
Your Current Organism:
Methanoregula boonei
NCBI taxonomy Id: 456442
Other names: Candidatus Methanoregula boonei 6A8, M. boonei 6A8, Methanoregula boonei 6A8, Methanoregula boonei str. 6A8, Methanoregula boonei strain 6A8, methanogenic archaeon 6A8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.