STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mboo_17072'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. (183 aa)    
Predicted Functional Partners:
cca
tRNA adenylyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
 
     0.880
rtcB
PFAM: protein of unknown function UPF0027; KEGG: mhu:Mhun_3181 protein of unknown function UPF0027; Belongs to the RtcB family.
 
   
 0.598
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
  
    0.546
Mboo_1709
TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; KEGG: mhu:Mhun_2811 ribonucleoside-triphosphate reductase, anaerobic.
       0.537
Mboo_1708
PFAM: glutaredoxin; KEGG: mtp:Mthe_0707 glutaredoxin.
       0.535
Mboo_0656
tryptophanyl-tRNA synthetase; KEGG: mhu:Mhun_1732 tryptophan--tRNA ligase; TIGRFAM: tryptophanyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase, class Ib.
     
 0.515
Mboo_0005
PFAM: protein of unknown function DUF343; KEGG: mbu:Mbur_1284 protein of unknown function DUF343.
 
     0.457
Mboo_1280
KEGG: mhu:Mhun_2796 metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region.
     
 0.453
Mboo_1593
KEGG: mhu:Mhun_1714 hypothetical protein; Belongs to the UPF0200 family.
 
     0.452
Mboo_0501
KEGG: mhu:Mhun_2355 MiaB-like tRNA modifying enzyme; TIGRFAM: RNA modification enzyme, MiaB family; MiaB-like tRNA modifying enzyme; PFAM: Radical SAM domain protein; Protein of unknown function UPF0004-like; SMART: Elongator protein 3/MiaB/NifB.
     
 0.444
Your Current Organism:
Methanoregula boonei
NCBI taxonomy Id: 456442
Other names: Candidatus Methanoregula boonei 6A8, M. boonei 6A8, Methanoregula boonei 6A8, Methanoregula boonei str. 6A8, Methanoregula boonei strain 6A8, methanogenic archaeon 6A8
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