STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mboo_1898PFAM: CBS domain containing protein; ParB domain protein nuclease; KEGG: mhu:Mhun_2618 CBS. (270 aa)    
Predicted Functional Partners:
Mboo_1577
KEGG: mhu:Mhun_0959 ATPases involved in chromosome partitioning-like.
  
 
 0.971
Mboo_0887
PFAM: response regulator receiver; KEGG: sat:SYN_00875 response regulator containing a CheY-like receiver domain and an HD-GYP domain.
  
 
 0.812
pcn
Proliferating cell nuclear antigen, PCNA; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family.
 
   
 0.666
Mboo_0527
KEGG: mhu:Mhun_2258 cell division GTPase-like.
 
 
 0.661
cetZ
Tubulin/FtsZ, GTPase; Involved in cell shape control; Belongs to the CetZ family.
 
 
 0.617
smc
Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.
 
 
 0.605
Mboo_0037
Hypothetical protein; KEGG: mhu:Mhun_2411 peptidase S26B, signal peptidase.
 
  
 0.595
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
 
  
 0.567
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
 
  
 0.537
Mboo_2054
PFAM: aminotransferase, class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; phosphoadenosine phosphosulfate reductase; KEGG: mhu:Mhun_2219 phosphoadenosine phosphosulfate reductase.
  
    0.533
Your Current Organism:
Methanoregula boonei
NCBI taxonomy Id: 456442
Other names: Candidatus Methanoregula boonei 6A8, M. boonei 6A8, Methanoregula boonei 6A8, Methanoregula boonei str. 6A8, Methanoregula boonei strain 6A8, methanogenic archaeon 6A8
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