STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mboo_1954KEGG: mhu:Mhun_1131 hypothetical protein. (244 aa)    
Predicted Functional Partners:
priS
Putative DNA primase, small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer s [...]
     
 0.846
Mboo_1828
PFAM: phosphoesterase, RecJ domain protein; phosphoesterase, DHHA1; KEGG: mhu:Mhun_2276 phosphoesterase, RecJ-like.
   
 
 0.821
Mboo_2236
PFAM: phosphoesterase, RecJ domain protein; phosphoesterase, DHHA1; KEGG: mhu:Mhun_2510 phosphoesterase, RecJ-like.
   
 
 0.821
Mboo_1956
KEGG: mhu:Mhun_1133 histone acetyltransferase, ELP3 family; TIGRFAM: histone acetyltransferase, ELP3 family; PFAM: GCN5-related N-acetyltransferase; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB.
       0.815
polB
DNA-directed DNA polymerase; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family.
    
 
 0.807
Mboo_1957
KEGG: mhu:Mhun_1134 protein of unknown function UPF0058.
  
    0.753
rpl44e
Ribosomal protein L44E; Binds to the 23S rRNA.
  
    0.654
Mboo_1951
PFAM: RNA binding S1 domain protein; translation initiation factor 2, alpha subunit; KEGG: mhu:Mhun_1128 translation initiation factor 2, alpha subunit.
       0.615
rps27e
PFAM: Ribosomal protein S27E; KEGG: mhu:Mhun_1129 ribosomal protein S27E.
       0.615
pcn
Proliferating cell nuclear antigen, PCNA; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. Belongs to the PCNA family.
  
  
 0.532
Your Current Organism:
Methanoregula boonei
NCBI taxonomy Id: 456442
Other names: Candidatus Methanoregula boonei 6A8, M. boonei 6A8, Methanoregula boonei 6A8, Methanoregula boonei str. 6A8, Methanoregula boonei strain 6A8, methanogenic archaeon 6A8
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