STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadAQuinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (302 aa)    
Predicted Functional Partners:
Mboo_0499
Nicotinate-nucleotide pyrophosphorylase; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family.
 
 0.999
Mboo_0500
Aspartate dehydrogenase; PFAM: oxidoreductase domain protein; dihydrodipicolinate reductase; aspartate dehydrogenase; homoserine dehydrogenase, NAD-binding; KEGG: mhu:Mhun_2354 aspartate dehydrogenase.
    
 0.945
Mboo_0086
PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mhu:Mhun_3053 succinate dehydrogenase.
   
 0.875
Mboo_1982
KEGG: mac:MA2721 serine O-acetyltransferase / hypothetical protein (multi-domain); TIGRFAM: serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; protein of unknown function DUF59.
  
    0.818
Mboo_1800
PFAM: HhH-GPD family protein; KEGG: mbu:Mbur_1875 DNA repair protein, HhH-GPD family.
      0.696
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
 
  
 0.654
Mboo_2120
PFAM: thiamineS protein.
  
    0.623
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
  
  
 0.615
Mboo_2121
PFAM: PP-loop domain protein; KEGG: mba:Mbar_A2672 hypothetical protein.
     
 0.603
Mboo_0356
PFAM: aminotransferase, class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: gvi:gll4384 cysteine desulfurase.
  
  
 0.573
Your Current Organism:
Methanoregula boonei
NCBI taxonomy Id: 456442
Other names: Candidatus Methanoregula boonei 6A8, M. boonei 6A8, Methanoregula boonei 6A8, Methanoregula boonei str. 6A8, Methanoregula boonei strain 6A8, methanogenic archaeon 6A8
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