STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mboo_2227PFAM: protein of unknown function DUF81; KEGG: sfu:Sfum_1521 protein of unknown function DUF81. (257 aa)    
Predicted Functional Partners:
Mboo_2226
PFAM: isochorismatase hydrolase; KEGG: mhu:Mhun_0141 isochorismatase hydrolase.
       0.650
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
  
  
 0.480
Mboo_2054
PFAM: aminotransferase, class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; phosphoadenosine phosphosulfate reductase; KEGG: mhu:Mhun_2219 phosphoadenosine phosphosulfate reductase.
  
  
 0.439
Mboo_1982
KEGG: mac:MA2721 serine O-acetyltransferase / hypothetical protein (multi-domain); TIGRFAM: serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; protein of unknown function DUF59.
  
    0.418
msrA
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
  
 0.409
Mboo_0782
Multi-sensor signal transduction histidine kinase; KEGG: mhu:Mhun_1958 putative PAS/PAC sensor protein; TIGRFAM: PAS sensor protein; PFAM: extracellular solute-binding protein, family 3; ATP-binding region, ATPase domain protein domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
  
 0.400
Your Current Organism:
Methanoregula boonei
NCBI taxonomy Id: 456442
Other names: Candidatus Methanoregula boonei 6A8, M. boonei 6A8, Methanoregula boonei 6A8, Methanoregula boonei str. 6A8, Methanoregula boonei strain 6A8, methanogenic archaeon 6A8
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