STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pgk-2PFAM: phosphoglycerate kinase; KEGG: mhu:Mhun_1194 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (404 aa)    
Predicted Functional Partners:
Mboo_1283
PFAM: glyceraldehyde 3-phosphate dehydrogenase; KEGG: cya:CYA_0020 glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 0.994
gap
KEGG: mhu:Mhun_2462 glyceraldehyde-3-phosphate dehydrogenase, type II; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type II; PFAM: glyceraldehyde 3-phosphate dehydrogenase; dihydrodipicolinate reductase.
 
 0.994
gpmA
Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
 0.976
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 
 0.968
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 
 0.945
Mboo_0678
Proposed homoserine kinase; KEGG: mhu:Mhun_0447 phosphonopyruvate decarboxylase-related protein; TIGRFAM: phosphonopyruvate decarboxylase-related protein; proposed homoserine kinase; PFAM: metalloenzyme domain protein.
    
 0.924
Mboo_0932
Enolase; KEGG: deh:cbdb_A573 enolase.
  
 
 0.924
Mboo_1611
KEGG: mbu:Mbur_1969 fructose-bisphosphate aldolase, class-II, putative.
  
 
 0.884
Mboo_1399
TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase, NAD - binding; Semialdehyde dehydrogenase, dimerisation region; KEGG: mhu:Mhun_1495 aspartate-semialdehyde dehydrogenase.
  
 
 0.801
rpl4
Ribosomal protein L4/L1e; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
  
 
 0.794
Your Current Organism:
Methanoregula boonei
NCBI taxonomy Id: 456442
Other names: Candidatus Methanoregula boonei 6A8, M. boonei 6A8, Methanoregula boonei 6A8, Methanoregula boonei str. 6A8, Methanoregula boonei strain 6A8, methanogenic archaeon 6A8
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