STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glgPGlycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (837 aa)    
Predicted Functional Partners:
glgC
Glucose-1-phosphate adenylyltransferase small subunit; ADP-glucose synthase; ADP-glucose pyrophosphorylase; AGPASE B; Alpha-D-glucose-1-phosphate adenyl transferase; ADPGlc PPase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
 
 
 0.995
malQ
4-alpha-glucanotransferase; Amylomaltase; Disproportionating enzyme; D-enzyme); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.990
glgA
Putative glycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose.
 
  
 0.977
galU1
UTP--glucose-1-phosphate uridylyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 
 0.937
ABZ98246.1
Putative glycoside hydrolase, family 57; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the glycosyl hydrolase 57 family.
    
 0.923
eno
Enolase (2-phosphoglycerate dehydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 
 0.846
pfkA
Diphosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.
  
 
 0.827
pgi
GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GPI family.
  
  
 0.787
ABZ97054.1
Putative two-component response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
       0.759
ABZ97052.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.754
Your Current Organism:
Leptospira biflexa
NCBI taxonomy Id: 456481
Other names: L. biflexa serovar Patoc strain 'Patoc 1 (Paris)', Leptospira biflexa serovar Patoc str. ATCC 23582, Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)', Leptospira biflexa serovar Patoc strain Patoc 1
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