node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABZ97541.1 | ispD | LEPBI_I1433 | LEPBI_I1435 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.733 |
ABZ97541.1 | lysA | LEPBI_I1433 | LEPBI_I1434 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Diaminopimelate decarboxylase (DAP decarboxylase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.768 |
ABZ97541.1 | murE | LEPBI_I1433 | LEPBI_I1760 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.695 |
dapA | dapB | LEPBI_I0733 | LEPBI_I0734 | Dihydrodipicolinate synthase (DHDPS); Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Dihydrodipicolinate reductase (DHPR); Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.999 |
dapA | dapF | LEPBI_I0733 | LEPBI_I0585 | Dihydrodipicolinate synthase (DHDPS); Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Diaminopimelate epimerase (DAP epimerase); Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.667 |
dapA | lysA | LEPBI_I0733 | LEPBI_I1434 | Dihydrodipicolinate synthase (DHDPS); Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Diaminopimelate decarboxylase (DAP decarboxylase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.838 |
dapA | lysC | LEPBI_I0733 | LEPBI_I0187 | Dihydrodipicolinate synthase (DHDPS); Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Aspartokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartokinase family. | 0.743 |
dapB | dapA | LEPBI_I0734 | LEPBI_I0733 | Dihydrodipicolinate reductase (DHPR); Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | Dihydrodipicolinate synthase (DHDPS); Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.999 |
dapB | dapE | LEPBI_I0734 | LEPBI_I3358 | Dihydrodipicolinate reductase (DHPR); Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | Succinyl-diaminopimelate desuccinylase (SDAP); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.738 |
dapB | dapF | LEPBI_I0734 | LEPBI_I0585 | Dihydrodipicolinate reductase (DHPR); Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | Diaminopimelate epimerase (DAP epimerase); Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.823 |
dapB | lysA | LEPBI_I0734 | LEPBI_I1434 | Dihydrodipicolinate reductase (DHPR); Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | Diaminopimelate decarboxylase (DAP decarboxylase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.857 |
dapB | lysC | LEPBI_I0734 | LEPBI_I0187 | Dihydrodipicolinate reductase (DHPR); Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | Aspartokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartokinase family. | 0.698 |
dapE | dapB | LEPBI_I3358 | LEPBI_I0734 | Succinyl-diaminopimelate desuccinylase (SDAP); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Dihydrodipicolinate reductase (DHPR); Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.738 |
dapE | dapF | LEPBI_I3358 | LEPBI_I0585 | Succinyl-diaminopimelate desuccinylase (SDAP); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Diaminopimelate epimerase (DAP epimerase); Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.715 |
dapE | lysA | LEPBI_I3358 | LEPBI_I1434 | Succinyl-diaminopimelate desuccinylase (SDAP); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Diaminopimelate decarboxylase (DAP decarboxylase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.711 |
dapF | dapA | LEPBI_I0585 | LEPBI_I0733 | Diaminopimelate epimerase (DAP epimerase); Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Dihydrodipicolinate synthase (DHDPS); Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.667 |
dapF | dapB | LEPBI_I0585 | LEPBI_I0734 | Diaminopimelate epimerase (DAP epimerase); Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Dihydrodipicolinate reductase (DHPR); Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.823 |
dapF | dapE | LEPBI_I0585 | LEPBI_I3358 | Diaminopimelate epimerase (DAP epimerase); Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Succinyl-diaminopimelate desuccinylase (SDAP); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.715 |
dapF | lysA | LEPBI_I0585 | LEPBI_I1434 | Diaminopimelate epimerase (DAP epimerase); Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Diaminopimelate decarboxylase (DAP decarboxylase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.984 |
dapF | lysC | LEPBI_I0585 | LEPBI_I0187 | Diaminopimelate epimerase (DAP epimerase); Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Aspartokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartokinase family. | 0.569 |