STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABZ97811.1Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (154 aa)    
Predicted Functional Partners:
ftsQ
Cell division protein FtsQ; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; factor.
   
 
 0.938
eno
Enolase (2-phosphoglycerate dehydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
    0.873
clpP1
ATP-dependent Clp protease proteolytic subunit (ATP-dependent Clp protease proteolytic subunit); Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
       0.862
ABZ97813.1
Putative hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.862
ABZ97814.1
Putative protease TldD; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.770
ABZ97815.1
Putative protease TldE (PmbA); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.770
ABZ97816.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.770
ABZ97817.1
Hypothetical protein; No homology to any previously reported sequences.
       0.723
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
       0.714
ABZ97808.1
Hypothetical protein; No homology to any previously reported sequences.
       0.685
Your Current Organism:
Leptospira biflexa
NCBI taxonomy Id: 456481
Other names: L. biflexa serovar Patoc strain 'Patoc 1 (Paris)', Leptospira biflexa serovar Patoc str. ATCC 23582, Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)', Leptospira biflexa serovar Patoc strain Patoc 1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.