STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
serCPhosphoserine aminotransferase (PSAT); Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (365 aa)    
Predicted Functional Partners:
serA2
D-3-phosphoglycerate dehydrogenase (PGDH); Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.984
serA1
D-3-phosphoglycerate dehydrogenase (PGDH); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.984
thrC
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
   
 0.947
serB
PSP; O-phosphoserine phosphohydrolase; PSPase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.944
pheA
P-protein; Includes: chorismate mutase (CM); prephenate dehydratase (PDT); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
 0.930
pdxA
4-hydroxythreonine-4-phosphate dehydrogenase (4-(phosphohydroxy)-L-threonine dehydrogenase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the PdxA family.
     
 0.918
cysK1
Cysteine synthase A; O-acetylserine sulfhydrylase; O-acetylserine (Thiol)-lyase; CSase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.912
cysM
Cysteine synthase B; O-acetylserine sulfhydrylase B; O-acetylserine (Thiol)-lyase B; CSase B); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.912
cysK2
Cysteine synthase A; O-acetylserine sulfhydrylase; O-acetylserine (Thiol)-lyase; CSase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.912
ABZ98458.1
Hypothetical protein; No homology to any previously reported sequences.
       0.862
Your Current Organism:
Leptospira biflexa
NCBI taxonomy Id: 456481
Other names: L. biflexa serovar Patoc strain 'Patoc 1 (Paris)', Leptospira biflexa serovar Patoc str. ATCC 23582, Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)', Leptospira biflexa serovar Patoc strain Patoc 1
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