node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABZ98689.1 | cdsA | LEPBI_I2610 | LEPBI_I2612 | Putative membrane-associated Zn-dependent metalloprotease, M50B family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.919 |
ABZ98689.1 | dxr | LEPBI_I2610 | LEPBI_I2611 | Putative membrane-associated Zn-dependent metalloprotease, M50B family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase 2; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.929 |
ABZ98689.1 | dxs | LEPBI_I2610 | LEPBI_I2605 | Putative membrane-associated Zn-dependent metalloprotease, M50B family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.563 |
ABZ98689.1 | frr | LEPBI_I2610 | LEPBI_I2614 | Putative membrane-associated Zn-dependent metalloprotease, M50B family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Ribosome recycling factor (Ribosome releasing factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.841 |
ABZ98689.1 | proS | LEPBI_I2610 | LEPBI_I2609 | Putative membrane-associated Zn-dependent metalloprotease, M50B family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Prolyl-tRNA synthetase (Proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' ed [...] | 0.891 |
ABZ98689.1 | pyrH | LEPBI_I2610 | LEPBI_I2615 | Putative membrane-associated Zn-dependent metalloprotease, M50B family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.877 |
ABZ98689.1 | tsf | LEPBI_I2610 | LEPBI_I2616 | Putative membrane-associated Zn-dependent metalloprotease, M50B family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Elongation factor Ts (EF-Ts); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.825 |
ABZ98689.1 | uppS | LEPBI_I2610 | LEPBI_I2613 | Putative membrane-associated Zn-dependent metalloprotease, M50B family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Undecaprenyl pyrophosphate synthetase (di-trans,poly-cis-decaprenylcistransferase); Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.940 |
cdsA | ABZ98689.1 | LEPBI_I2612 | LEPBI_I2610 | Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Putative membrane-associated Zn-dependent metalloprotease, M50B family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 0.919 |
cdsA | dxr | LEPBI_I2612 | LEPBI_I2611 | Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase 2; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.952 |
cdsA | dxs | LEPBI_I2612 | LEPBI_I2605 | Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.596 |
cdsA | frr | LEPBI_I2612 | LEPBI_I2614 | Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Ribosome recycling factor (Ribosome releasing factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.911 |
cdsA | proS | LEPBI_I2612 | LEPBI_I2609 | Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Prolyl-tRNA synthetase (Proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' ed [...] | 0.797 |
cdsA | pyrH | LEPBI_I2612 | LEPBI_I2615 | Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.928 |
cdsA | tsf | LEPBI_I2612 | LEPBI_I2616 | Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Elongation factor Ts (EF-Ts); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.876 |
cdsA | uppS | LEPBI_I2612 | LEPBI_I2613 | Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Undecaprenyl pyrophosphate synthetase (di-trans,poly-cis-decaprenylcistransferase); Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.984 |
dxr | ABZ98689.1 | LEPBI_I2611 | LEPBI_I2610 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase 2; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Putative membrane-associated Zn-dependent metalloprotease, M50B family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 0.929 |
dxr | cdsA | LEPBI_I2611 | LEPBI_I2612 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase 2; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.952 |
dxr | dxs | LEPBI_I2611 | LEPBI_I2605 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase 2; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.991 |
dxr | frr | LEPBI_I2611 | LEPBI_I2614 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase 2; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Ribosome recycling factor (Ribosome releasing factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.887 |