STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ctaDCytochrome c oxidase polypeptide I (Cytochrome aa3 subunit 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the heme-copper respiratory oxidase family. (537 aa)    
Predicted Functional Partners:
ctaE
Cytochrome c oxidase polypeptide III (Cytochrome aa3 subunit 3; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.999
ctaC
Cytochrome c oxidase polypeptide II (Cytochrome aa3 subunit 2; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
 
 0.999
ctaB
Protoheme IX farnesyltransferase (Heme O synthase); Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
 
 0.998
norE
Nitric oxide reductase subunit E; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.996
ctaF
Cytochrome c oxidase polypeptide IVB (Cytochrome aa3 subunit 4B; Function of homologous gene experimentally demonstrated in an other organism; putative enzyme.
 
  
 0.994
nuoM
NADH dehydrogenase I, chain M; NDH-1, chain M; NUO13); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.991
nuoH
NADH-quinone oxidoreductase, chain H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.
  
 
 0.971
ABZ99599.1
Putative cytochrome c oxidase, subunit III; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 0.971
ABZ98763.1
Putative protein involved in the biogenesis of respiratory; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
  
 0.965
norC
Nitric oxide reductase, cytochrome c-containing subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.959
Your Current Organism:
Leptospira biflexa
NCBI taxonomy Id: 456481
Other names: L. biflexa serovar Patoc strain 'Patoc 1 (Paris)', Leptospira biflexa serovar Patoc str. ATCC 23582, Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)', Leptospira biflexa serovar Patoc strain Patoc 1
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