STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RBR1Retinoblastoma-related protein 1; Regulator of biological processes that recruits a histone deacetylase to control gene transcription. May play a role in the entry into mitosis, negatively regulating the cell proliferation. Formation of stable complexes with geminiviridae replication-associated proteins may create a cellular environment which favors viral DNA replication (By similarity); Belongs to the retinoblastoma protein (RB) family. (957 aa)    
Predicted Functional Partners:
A0A3B5XXS6
Uncharacterized protein; Involved in the regulation of the G1/S transition. Increases the DNA binding activity of E2F proteins after heterodimerization. Belongs to the E2F/DP family.
   
 0.968
A0A3B5YVB5
Uncharacterized protein; Involved in the regulation of the G1/S transition. Increases the DNA binding activity of E2F proteins after heterodimerization. Belongs to the E2F/DP family.
   
 0.968
A0A3B5ZRQ1
Uncharacterized protein; Involved in the regulation of the G1/S transition. Increases the DNA binding activity of E2F proteins after heterodimerization. Belongs to the E2F/DP family.
   
 0.968
A0A3B6HS36
Uncharacterized protein; Involved in the regulation of the G1/S transition. Increases the DNA binding activity of E2F proteins after heterodimerization. Belongs to the E2F/DP family.
   
 0.968
A0A3B6IWY5
Uncharacterized protein; Involved in the regulation of the G1/S transition. Increases the DNA binding activity of E2F proteins after heterodimerization. Belongs to the E2F/DP family.
   
 0.968
A0A3B6JLV6
Uncharacterized protein; Involved in the regulation of the G1/S transition. Increases the DNA binding activity of E2F proteins after heterodimerization. Belongs to the E2F/DP family.
   
 0.968
A0A3B6EIT0
Uncharacterized protein.
   
 0.967
A0A3B6FPW4
Uncharacterized protein.
   
 0.967
A0A3B6GY31
Uncharacterized protein.
   
 0.967
A0A077RTD0
SANT domain-containing protein.
   
 0.964
Your Current Organism:
Triticum aestivum
NCBI taxonomy Id: 4565
Other names: Canadian hard winter wheat, T. aestivum, Triticum aestivum L., Triticum aestivum subsp. aestivum, Triticum vulgare, Triticum vulgare L., Triticum vulgare Vill., nom. illeg., bread wheat, common wheat, wheat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.