Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ANS87704.1 | metB | VSVS12_04004 | VSVS12_00368 | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family; KEGG: pwa:Pecwa_1367 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase. | Catalyzes the formation of L-cystathionine from O- succinyl-L-homoserine (OSHS) and L-cysteine, via a gamma- replacement reaction. In the absence of thiol, catalyzes gamma- elimination to form 2-oxobutanoate, succinate and ammonia; Belongs to the trans-sulfuration enzymes family; KEGG: ctu:CTU_01800 cystathionine gamma-synthase. | 0.938 |
| ANS87704.1 | metB-2 | VSVS12_04004 | VSVS12_01088 | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family; KEGG: pwa:Pecwa_1367 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase. | Catalyzes the formation of L-cystathionine from O- succinyl-L-homoserine (OSHS) and L-cysteine, via a gamma- replacement reaction. In the absence of thiol, catalyzes gamma- elimination to form 2-oxobutanoate, succinate and ammonia (By similarity); Belongs to the trans-sulfuration enzymes family; KEGG: pmr:PMI3223 cystathionine gamma-synthase. | 0.938 |
| ANS87704.1 | metC | VSVS12_04004 | VSVS12_00085 | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family; KEGG: pwa:Pecwa_1367 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase. | Cystathionine beta-lyase; Belongs to the trans-sulfuration enzymes family; KEGG: spe:Spro_4212 cystathionine beta-lyase. | 0.938 |
| ANS87704.1 | metC-2 | VSVS12_04004 | VSVS12_02040 | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family; KEGG: pwa:Pecwa_1367 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase. | Cystathionine beta-lyase; Belongs to the trans-sulfuration enzymes family; KEGG: vtu:IX91_06075 cystathionine beta-lyase; overlaps another CDS with the same product name. | 0.938 |
| ANS87704.1 | metE | VSVS12_04004 | VSVS12_01545 | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family; KEGG: pwa:Pecwa_1367 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase. | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.906 |
| ANS87704.1 | metF | VSVS12_04004 | VSVS12_00366 | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family; KEGG: pwa:Pecwa_1367 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase. | Methylenetetrahydrofolate reductase required to generate the methyl groups necessary for methionine synthetase to convert homocysteine to methionine; Belongs to the methylenetetrahydrofolate reductase family; KEGG: vvu:VV1_1366 methylenetetrahydrofolate reductase (NADPH). | 0.784 |
| ANS87704.1 | metH | VSVS12_04004 | VSVS12_00533 | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family; KEGG: pwa:Pecwa_1367 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.974 |
| ANS87704.1 | metL | VSVS12_04004 | VSVS12_00367 | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family; KEGG: pwa:Pecwa_1367 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase. | Aspartate kinase; In the N-terminal sectio; belongs to the aspartokinase family; In the C-terminal sectio; belongs to the homoserine dehydrogenase family; KEGG: vpa:VP2764 bifunctional aspartokinase / homoserine dehydrogenase 2. | 0.919 |
| ANS87704.1 | thrA | VSVS12_04004 | VSVS12_02623 | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family; KEGG: pwa:Pecwa_1367 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase. | Aspartate kinase; In the N-terminal sectio; belongs to the aspartokinase family; In the C-terminal sectio; belongs to the homoserine dehydrogenase family; Contains 2 ACT domains; KEGG: eco:b0002 bifunctional aspartokinase / homoserine dehydrogenase 1. | 0.919 |
| gcvT | metF | VSVS12_04281 | VSVS12_00366 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family; KEGG: dat:HRM2_25000 aminomethyltransferase. | Methylenetetrahydrofolate reductase required to generate the methyl groups necessary for methionine synthetase to convert homocysteine to methionine; Belongs to the methylenetetrahydrofolate reductase family; KEGG: vvu:VV1_1366 methylenetetrahydrofolate reductase (NADPH). | 0.939 |
| gcvT | metH | VSVS12_04281 | VSVS12_00533 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family; KEGG: dat:HRM2_25000 aminomethyltransferase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.951 |
| metB | ANS87704.1 | VSVS12_00368 | VSVS12_04004 | Catalyzes the formation of L-cystathionine from O- succinyl-L-homoserine (OSHS) and L-cysteine, via a gamma- replacement reaction. In the absence of thiol, catalyzes gamma- elimination to form 2-oxobutanoate, succinate and ammonia; Belongs to the trans-sulfuration enzymes family; KEGG: ctu:CTU_01800 cystathionine gamma-synthase. | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family; KEGG: pwa:Pecwa_1367 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase. | 0.938 |
| metB | metB-2 | VSVS12_00368 | VSVS12_01088 | Catalyzes the formation of L-cystathionine from O- succinyl-L-homoserine (OSHS) and L-cysteine, via a gamma- replacement reaction. In the absence of thiol, catalyzes gamma- elimination to form 2-oxobutanoate, succinate and ammonia; Belongs to the trans-sulfuration enzymes family; KEGG: ctu:CTU_01800 cystathionine gamma-synthase. | Catalyzes the formation of L-cystathionine from O- succinyl-L-homoserine (OSHS) and L-cysteine, via a gamma- replacement reaction. In the absence of thiol, catalyzes gamma- elimination to form 2-oxobutanoate, succinate and ammonia (By similarity); Belongs to the trans-sulfuration enzymes family; KEGG: pmr:PMI3223 cystathionine gamma-synthase. | 0.909 |
| metB | metC | VSVS12_00368 | VSVS12_00085 | Catalyzes the formation of L-cystathionine from O- succinyl-L-homoserine (OSHS) and L-cysteine, via a gamma- replacement reaction. In the absence of thiol, catalyzes gamma- elimination to form 2-oxobutanoate, succinate and ammonia; Belongs to the trans-sulfuration enzymes family; KEGG: ctu:CTU_01800 cystathionine gamma-synthase. | Cystathionine beta-lyase; Belongs to the trans-sulfuration enzymes family; KEGG: spe:Spro_4212 cystathionine beta-lyase. | 0.925 |
| metB | metC-2 | VSVS12_00368 | VSVS12_02040 | Catalyzes the formation of L-cystathionine from O- succinyl-L-homoserine (OSHS) and L-cysteine, via a gamma- replacement reaction. In the absence of thiol, catalyzes gamma- elimination to form 2-oxobutanoate, succinate and ammonia; Belongs to the trans-sulfuration enzymes family; KEGG: ctu:CTU_01800 cystathionine gamma-synthase. | Cystathionine beta-lyase; Belongs to the trans-sulfuration enzymes family; KEGG: vtu:IX91_06075 cystathionine beta-lyase; overlaps another CDS with the same product name. | 0.923 |
| metB | metE | VSVS12_00368 | VSVS12_01545 | Catalyzes the formation of L-cystathionine from O- succinyl-L-homoserine (OSHS) and L-cysteine, via a gamma- replacement reaction. In the absence of thiol, catalyzes gamma- elimination to form 2-oxobutanoate, succinate and ammonia; Belongs to the trans-sulfuration enzymes family; KEGG: ctu:CTU_01800 cystathionine gamma-synthase. | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.938 |
| metB | metF | VSVS12_00368 | VSVS12_00366 | Catalyzes the formation of L-cystathionine from O- succinyl-L-homoserine (OSHS) and L-cysteine, via a gamma- replacement reaction. In the absence of thiol, catalyzes gamma- elimination to form 2-oxobutanoate, succinate and ammonia; Belongs to the trans-sulfuration enzymes family; KEGG: ctu:CTU_01800 cystathionine gamma-synthase. | Methylenetetrahydrofolate reductase required to generate the methyl groups necessary for methionine synthetase to convert homocysteine to methionine; Belongs to the methylenetetrahydrofolate reductase family; KEGG: vvu:VV1_1366 methylenetetrahydrofolate reductase (NADPH). | 0.778 |
| metB | metH | VSVS12_00368 | VSVS12_00533 | Catalyzes the formation of L-cystathionine from O- succinyl-L-homoserine (OSHS) and L-cysteine, via a gamma- replacement reaction. In the absence of thiol, catalyzes gamma- elimination to form 2-oxobutanoate, succinate and ammonia; Belongs to the trans-sulfuration enzymes family; KEGG: ctu:CTU_01800 cystathionine gamma-synthase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.970 |
| metB | metL | VSVS12_00368 | VSVS12_00367 | Catalyzes the formation of L-cystathionine from O- succinyl-L-homoserine (OSHS) and L-cysteine, via a gamma- replacement reaction. In the absence of thiol, catalyzes gamma- elimination to form 2-oxobutanoate, succinate and ammonia; Belongs to the trans-sulfuration enzymes family; KEGG: ctu:CTU_01800 cystathionine gamma-synthase. | Aspartate kinase; In the N-terminal sectio; belongs to the aspartokinase family; In the C-terminal sectio; belongs to the homoserine dehydrogenase family; KEGG: vpa:VP2764 bifunctional aspartokinase / homoserine dehydrogenase 2. | 0.977 |
| metB | thrA | VSVS12_00368 | VSVS12_02623 | Catalyzes the formation of L-cystathionine from O- succinyl-L-homoserine (OSHS) and L-cysteine, via a gamma- replacement reaction. In the absence of thiol, catalyzes gamma- elimination to form 2-oxobutanoate, succinate and ammonia; Belongs to the trans-sulfuration enzymes family; KEGG: ctu:CTU_01800 cystathionine gamma-synthase. | Aspartate kinase; In the N-terminal sectio; belongs to the aspartokinase family; In the C-terminal sectio; belongs to the homoserine dehydrogenase family; Contains 2 ACT domains; KEGG: eco:b0002 bifunctional aspartokinase / homoserine dehydrogenase 1. | 0.906 |
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