node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANS84480.1 | gluQ | VSVS12_00683 | VSVS12_00682 | Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression; Belongs to the DksA family; Contains 1 dksA C4-type zinc finger. | Glutamyl-Q tRNA(Asp) synthetase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. | 0.657 |
ANS84480.1 | hrpB | VSVS12_00683 | VSVS12_00685 | Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression; Belongs to the DksA family; Contains 1 dksA C4-type zinc finger. | RNA helicase; Belongs to the DEAD box helicase family; Contains 1 helicase ATP-binding domain; Contains 1 helicase C-terminal domain; KEGG: vph:VPUCM_2588 ATP-dependent helicase HrpB. | 0.425 |
ANS84480.1 | sfsA | VSVS12_00683 | VSVS12_00684 | Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression; Belongs to the DksA family; Contains 1 dksA C4-type zinc finger. | Sugar fermentation stimulation protein like protein; Belongs to the SfsA family. | 0.585 |
ANS84484.1 | hrpB | VSVS12_00687 | VSVS12_00685 | Lysophospholipase NTE1; Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis. Responsible for the rapid PC turnover in response to inositol, elevated temperatures, or when choline is present in the growth medium (By similarity); Belongs to the NTE family; Contains 2 cyclic nucleotide-binding domains; Contains 1 patatin domain. | RNA helicase; Belongs to the DEAD box helicase family; Contains 1 helicase ATP-binding domain; Contains 1 helicase C-terminal domain; KEGG: vph:VPUCM_2588 ATP-dependent helicase HrpB. | 0.570 |
ANS84484.1 | mrcB | VSVS12_00687 | VSVS12_00686 | Lysophospholipase NTE1; Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis. Responsible for the rapid PC turnover in response to inositol, elevated temperatures, or when choline is present in the growth medium (By similarity); Belongs to the NTE family; Contains 2 cyclic nucleotide-binding domains; Contains 1 patatin domain. | Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.635 |
ANS84484.1 | sfsA | VSVS12_00687 | VSVS12_00684 | Lysophospholipase NTE1; Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis. Responsible for the rapid PC turnover in response to inositol, elevated temperatures, or when choline is present in the growth medium (By similarity); Belongs to the NTE family; Contains 2 cyclic nucleotide-binding domains; Contains 1 patatin domain. | Sugar fermentation stimulation protein like protein; Belongs to the SfsA family. | 0.484 |
gluQ | ANS84480.1 | VSVS12_00682 | VSVS12_00683 | Glutamyl-Q tRNA(Asp) synthetase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. | Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression; Belongs to the DksA family; Contains 1 dksA C4-type zinc finger. | 0.657 |
gluQ | sfsA | VSVS12_00682 | VSVS12_00684 | Glutamyl-Q tRNA(Asp) synthetase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. | Sugar fermentation stimulation protein like protein; Belongs to the SfsA family. | 0.511 |
hrpB | ANS84480.1 | VSVS12_00685 | VSVS12_00683 | RNA helicase; Belongs to the DEAD box helicase family; Contains 1 helicase ATP-binding domain; Contains 1 helicase C-terminal domain; KEGG: vph:VPUCM_2588 ATP-dependent helicase HrpB. | Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression; Belongs to the DksA family; Contains 1 dksA C4-type zinc finger. | 0.425 |
hrpB | ANS84484.1 | VSVS12_00685 | VSVS12_00687 | RNA helicase; Belongs to the DEAD box helicase family; Contains 1 helicase ATP-binding domain; Contains 1 helicase C-terminal domain; KEGG: vph:VPUCM_2588 ATP-dependent helicase HrpB. | Lysophospholipase NTE1; Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis. Responsible for the rapid PC turnover in response to inositol, elevated temperatures, or when choline is present in the growth medium (By similarity); Belongs to the NTE family; Contains 2 cyclic nucleotide-binding domains; Contains 1 patatin domain. | 0.570 |
hrpB | mrcB | VSVS12_00685 | VSVS12_00686 | RNA helicase; Belongs to the DEAD box helicase family; Contains 1 helicase ATP-binding domain; Contains 1 helicase C-terminal domain; KEGG: vph:VPUCM_2588 ATP-dependent helicase HrpB. | Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.703 |
hrpB | sfsA | VSVS12_00685 | VSVS12_00684 | RNA helicase; Belongs to the DEAD box helicase family; Contains 1 helicase ATP-binding domain; Contains 1 helicase C-terminal domain; KEGG: vph:VPUCM_2588 ATP-dependent helicase HrpB. | Sugar fermentation stimulation protein like protein; Belongs to the SfsA family. | 0.604 |
mrcB | ANS84484.1 | VSVS12_00686 | VSVS12_00687 | Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | Lysophospholipase NTE1; Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis. Responsible for the rapid PC turnover in response to inositol, elevated temperatures, or when choline is present in the growth medium (By similarity); Belongs to the NTE family; Contains 2 cyclic nucleotide-binding domains; Contains 1 patatin domain. | 0.635 |
mrcB | hrpB | VSVS12_00686 | VSVS12_00685 | Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | RNA helicase; Belongs to the DEAD box helicase family; Contains 1 helicase ATP-binding domain; Contains 1 helicase C-terminal domain; KEGG: vph:VPUCM_2588 ATP-dependent helicase HrpB. | 0.703 |
mrcB | sfsA | VSVS12_00686 | VSVS12_00684 | Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | Sugar fermentation stimulation protein like protein; Belongs to the SfsA family. | 0.543 |
mutY-2 | sfsA | VSVS12_00567 | VSVS12_00684 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Sugar fermentation stimulation protein like protein; Belongs to the SfsA family. | 0.887 |
proA | sfsA | VSVS12_00851 | VSVS12_00684 | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | Sugar fermentation stimulation protein like protein; Belongs to the SfsA family. | 0.576 |
sfsA | ANS84480.1 | VSVS12_00684 | VSVS12_00683 | Sugar fermentation stimulation protein like protein; Belongs to the SfsA family. | Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression; Belongs to the DksA family; Contains 1 dksA C4-type zinc finger. | 0.585 |
sfsA | ANS84484.1 | VSVS12_00684 | VSVS12_00687 | Sugar fermentation stimulation protein like protein; Belongs to the SfsA family. | Lysophospholipase NTE1; Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis. Responsible for the rapid PC turnover in response to inositol, elevated temperatures, or when choline is present in the growth medium (By similarity); Belongs to the NTE family; Contains 2 cyclic nucleotide-binding domains; Contains 1 patatin domain. | 0.484 |
sfsA | gluQ | VSVS12_00684 | VSVS12_00682 | Sugar fermentation stimulation protein like protein; Belongs to the SfsA family. | Glutamyl-Q tRNA(Asp) synthetase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. | 0.511 |