STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANS84565.1Putative response regulatory protein; Contains 1 HTH LytTR-type DNA-binding domain; Contains 1 response regulatory domain. (244 aa)    
Predicted Functional Partners:
ANS84566.1
Histidine kinase; Member of the two-component regulatory system YehU/YehT, which may be involved in the stationary-phase control network. Activates YehT by phosphorylation (By similarity); Contains 1 histidine kinase domain; KEGG: eca:ECA4152 two-component system, LytT family, sensor kinase.
 
 
 0.976
ANS85152.1
Sensor protein LytS; Member of the two-component regulatory system LytS/LytT that probably regulates genes involved in cell wall metabolism. Contains 1 histidine kinase domain; KEGG: vfi:VF_A0733 null; Phosphotransferases with a nitrogenous group as acceptor.
 
  
 0.877
tyrA
Contains 1 chorismate mutase domain; Contains 1 prephenate/arogenate dehydrogenase domain; KEGG: aha:AHA_1655 chorismate mutase / prephenate dehydrogenase.
       0.520
aroF
3-deoxy-7-phosphoheptulonate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).
       0.496
ANS85365.1
Holin-like protein CidB; Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidAB proteins. When a cell is stressed by the addition of antibiotics or by other factors in the environment, the CidAB proteins possibly oligomerize within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized [...]
    
 0.430
ANS87253.1
Histidine kinase; Member of the two-component regulatory system CitT/CitS. Functions probably as a membrane-associated protein kinase that phosphorylates CitT in response to environmental citrate or Mg(2+)-citrate complex (By similarity); Contains 1 histidine kinase domain; Contains 1 PAS (PER-ARNT-SIM) domain; KEGG: ctc:CTC01524 two-component system, CitB family, sensor kinase.
 
   
 0.407
barA
Histidine kinase; Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system. Phosphorylates UvrY, probably via a four-step phosphorelay (By similarity); Contains 1 HAMP domain; Contains 1 histidine kinase domain; Contains 1 HPt domain; Contains 1 response regulatory domain; KEGG: vvu:VV1_1573 two-component system, NarL family, sensor histidine kinase BarA.
     
 0.405
Your Current Organism:
Vibrio scophthalmi
NCBI taxonomy Id: 45658
Other names: CAIM 75, CECT 4638, CIP 105211, LMG 19158, LMG:19158, V. scophthalmi, strain A089
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