| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ANS84574.1 | ANS84575.1 | VSVS12_00779 | VSVS12_00780 | Non-canonical purine NTP phosphatase; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. | Cyclic-guanylate-specific phosphodiesterase; Plays an essential role in the maintenance and the formation of the three-dimensional structure of the biofilms at the later stages of their development. Absence of mbaA promotes the accumulation of larger amount of biomass on the surfaces at later stage of development, results in the overproduction of an extracellular polymeric substance that accumulates in the matrix of biofilms. This yields biofilms lacking the typical structure consisting of pillars of cells separated by fluid filled channels; Contains 1 EAL domain; Contains 1 GGDEF doma [...] | 0.787 |
| ANS84574.1 | ANS84576.1 | VSVS12_00779 | VSVS12_00781 | Non-canonical purine NTP phosphatase; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. | Acts as a sensor of norspermidine and enhances biofilm formation. When complexed to norspermidine, could interact with the periplasmic portion of MbaA to regulate its enzymatic activity; Belongs to the bacterial solute-binding protein PotD/PotF family. | 0.787 |
| ANS84574.1 | ndk | VSVS12_00779 | VSVS12_00815 | Non-canonical purine NTP phosphatase; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.900 |
| ANS84574.1 | pheA | VSVS12_00779 | VSVS12_00782 | Non-canonical purine NTP phosphatase; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. | Chorismate mutase; Contains 1 ACT domain; Contains 1 chorismate mutase domain; Contains 1 prephenate dehydratase domain; KEGG: vch:VC0705 chorismate mutase / prephenate dehydratase. | 0.560 |
| ANS84575.1 | ANS84574.1 | VSVS12_00780 | VSVS12_00779 | Cyclic-guanylate-specific phosphodiesterase; Plays an essential role in the maintenance and the formation of the three-dimensional structure of the biofilms at the later stages of their development. Absence of mbaA promotes the accumulation of larger amount of biomass on the surfaces at later stage of development, results in the overproduction of an extracellular polymeric substance that accumulates in the matrix of biofilms. This yields biofilms lacking the typical structure consisting of pillars of cells separated by fluid filled channels; Contains 1 EAL domain; Contains 1 GGDEF doma [...] | Non-canonical purine NTP phosphatase; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. | 0.787 |
| ANS84575.1 | ANS84576.1 | VSVS12_00780 | VSVS12_00781 | Cyclic-guanylate-specific phosphodiesterase; Plays an essential role in the maintenance and the formation of the three-dimensional structure of the biofilms at the later stages of their development. Absence of mbaA promotes the accumulation of larger amount of biomass on the surfaces at later stage of development, results in the overproduction of an extracellular polymeric substance that accumulates in the matrix of biofilms. This yields biofilms lacking the typical structure consisting of pillars of cells separated by fluid filled channels; Contains 1 EAL domain; Contains 1 GGDEF doma [...] | Acts as a sensor of norspermidine and enhances biofilm formation. When complexed to norspermidine, could interact with the periplasmic portion of MbaA to regulate its enzymatic activity; Belongs to the bacterial solute-binding protein PotD/PotF family. | 0.808 |
| ANS84575.1 | pheA | VSVS12_00780 | VSVS12_00782 | Cyclic-guanylate-specific phosphodiesterase; Plays an essential role in the maintenance and the formation of the three-dimensional structure of the biofilms at the later stages of their development. Absence of mbaA promotes the accumulation of larger amount of biomass on the surfaces at later stage of development, results in the overproduction of an extracellular polymeric substance that accumulates in the matrix of biofilms. This yields biofilms lacking the typical structure consisting of pillars of cells separated by fluid filled channels; Contains 1 EAL domain; Contains 1 GGDEF doma [...] | Chorismate mutase; Contains 1 ACT domain; Contains 1 chorismate mutase domain; Contains 1 prephenate dehydratase domain; KEGG: vch:VC0705 chorismate mutase / prephenate dehydratase. | 0.507 |
| ANS84576.1 | ANS84574.1 | VSVS12_00781 | VSVS12_00779 | Acts as a sensor of norspermidine and enhances biofilm formation. When complexed to norspermidine, could interact with the periplasmic portion of MbaA to regulate its enzymatic activity; Belongs to the bacterial solute-binding protein PotD/PotF family. | Non-canonical purine NTP phosphatase; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. | 0.787 |
| ANS84576.1 | ANS84575.1 | VSVS12_00781 | VSVS12_00780 | Acts as a sensor of norspermidine and enhances biofilm formation. When complexed to norspermidine, could interact with the periplasmic portion of MbaA to regulate its enzymatic activity; Belongs to the bacterial solute-binding protein PotD/PotF family. | Cyclic-guanylate-specific phosphodiesterase; Plays an essential role in the maintenance and the formation of the three-dimensional structure of the biofilms at the later stages of their development. Absence of mbaA promotes the accumulation of larger amount of biomass on the surfaces at later stage of development, results in the overproduction of an extracellular polymeric substance that accumulates in the matrix of biofilms. This yields biofilms lacking the typical structure consisting of pillars of cells separated by fluid filled channels; Contains 1 EAL domain; Contains 1 GGDEF doma [...] | 0.808 |
| ANS84576.1 | pheA | VSVS12_00781 | VSVS12_00782 | Acts as a sensor of norspermidine and enhances biofilm formation. When complexed to norspermidine, could interact with the periplasmic portion of MbaA to regulate its enzymatic activity; Belongs to the bacterial solute-binding protein PotD/PotF family. | Chorismate mutase; Contains 1 ACT domain; Contains 1 chorismate mutase domain; Contains 1 prephenate dehydratase domain; KEGG: vch:VC0705 chorismate mutase / prephenate dehydratase. | 0.529 |
| ndk | ANS84574.1 | VSVS12_00815 | VSVS12_00779 | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Non-canonical purine NTP phosphatase; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. | 0.900 |
| pheA | ANS84574.1 | VSVS12_00782 | VSVS12_00779 | Chorismate mutase; Contains 1 ACT domain; Contains 1 chorismate mutase domain; Contains 1 prephenate dehydratase domain; KEGG: vch:VC0705 chorismate mutase / prephenate dehydratase. | Non-canonical purine NTP phosphatase; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. | 0.560 |
| pheA | ANS84575.1 | VSVS12_00782 | VSVS12_00780 | Chorismate mutase; Contains 1 ACT domain; Contains 1 chorismate mutase domain; Contains 1 prephenate dehydratase domain; KEGG: vch:VC0705 chorismate mutase / prephenate dehydratase. | Cyclic-guanylate-specific phosphodiesterase; Plays an essential role in the maintenance and the formation of the three-dimensional structure of the biofilms at the later stages of their development. Absence of mbaA promotes the accumulation of larger amount of biomass on the surfaces at later stage of development, results in the overproduction of an extracellular polymeric substance that accumulates in the matrix of biofilms. This yields biofilms lacking the typical structure consisting of pillars of cells separated by fluid filled channels; Contains 1 EAL domain; Contains 1 GGDEF doma [...] | 0.507 |
| pheA | ANS84576.1 | VSVS12_00782 | VSVS12_00781 | Chorismate mutase; Contains 1 ACT domain; Contains 1 chorismate mutase domain; Contains 1 prephenate dehydratase domain; KEGG: vch:VC0705 chorismate mutase / prephenate dehydratase. | Acts as a sensor of norspermidine and enhances biofilm formation. When complexed to norspermidine, could interact with the periplasmic portion of MbaA to regulate its enzymatic activity; Belongs to the bacterial solute-binding protein PotD/PotF family. | 0.529 |