STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metNLipoprotein-releasing system ATP-binding protein LolD; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (344 aa)    
Predicted Functional Partners:
ANS84689.1
Putative D-methionine-binding lipoprotein MetQ; This protein is a component of a D-methionine permease, a binding protein-dependent, ATP-driven transport system; Belongs to the NlpA lipoprotein family.
 
 0.999
ANS84690.1
Part of the binding-protein-dependent transport system for D-methionine. Probably responsible for the translocation of the substrate across the membrane (By similarity); Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily; Contains 1 ABC transmembrane type-1 domain.
 
 0.999
metA
Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family.
  
    0.710
ANS85693.1
ATP-binding/permease protein CydD; Somehow involved in the cytochrome D branch of aerobic respiration. Seems to be a component of a transport system (By similarity); Belongs to the ABC transporter superfamily. Cysteine exporter (TC 3. A. 1. 129. 1) family; Contains 1 ABC transmembrane type-1 domain; Contains 1 ABC transporter domain.
    
0.681
metF
Methylenetetrahydrofolate reductase required to generate the methyl groups necessary for methionine synthetase to convert homocysteine to methionine; Belongs to the methylenetetrahydrofolate reductase family; KEGG: vvu:VV1_1366 methylenetetrahydrofolate reductase (NADPH).
   
  
 0.637
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
  
 0.630
gmhB
D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase; Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position; Belongs to the GmhB family; KEGG: vch:VC0908 D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase.
       0.514
ANS85857.1
Proteases secretion ATP-binding protein PrtD; Involved in the secretion of proteases A, B, C and G. Belongs to the ABC transporter superfamily; Contains 1 ABC transmembrane type-1 domain; Contains 1 ABC transporter domain.
 
     
0.475
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
  
 0.437
ANS84693.1
Hypothetical protein.
       0.433
Your Current Organism:
Vibrio scophthalmi
NCBI taxonomy Id: 45658
Other names: CAIM 75, CECT 4638, CIP 105211, LMG 19158, LMG:19158, V. scophthalmi, strain A089
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