STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
vieACyclic-guanylate-specific phosphodiesterase; Photoreceptor which exists in two forms that are reversibly interconvertible by light: the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. Belongs to the phytochrome family; Contains 1 EAL domain; Contains 2 GAF domains; Contains 2 GGDEF domains; KEGG: vch:VC1652 c-di-GMP phosphodiesterase. (579 aa)    
Predicted Functional Partners:
arcB
Histidine kinase; Contains 1 GGDEF domain; KEGG: eca:ECA0314 two-component system, OmpR family, aerobic respiration control sensor histidine kinase ArcB.
 
 0.996
ANS85187.1
Ethylene receptor related to bacterial two-component regulators. Acts as negative regulator of ethylene signaling. May delay the transition from the vegetative stage to the floral stage by upregulating GI (GIGANTEA) and RCN1 and cause starch accumulation in stems by down-regulating the alpha-amylase AMY3D; Belongs to the ethylene receptor family; Contains 1 GAF domain; Contains 1 histidine kinase domain; Contains 1 response regulatory domain.
 
 
 0.991
evgS
Histidine kinase; Ethylene receptor related to bacterial two-component regulators. Acts as a redundant negative regulator of ethylene signaling. Belongs to the ethylene receptor family; Contains 1 GAF domain; Contains 1 histidine kinase domain; KEGG: van:VAA_03253 two-component system, NarL family, sensor histidine kinase EvgS.
  
 
 0.949
ANS87120.1
Histidine kinase; Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria. Contains 1 GGDEF domain; KEGG: gme:Gmet_2694 two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR.
 
 
 0.946
ANS85272.1
Protein AdrA; Contains 1 GGDEF domain.
 
 0.929
arcB-2
Histidine kinase; Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and Asp-576 (By similarity); Contains 1 histidine kinase domain; Contains 1 HPt domain; Contains 1 PAC (PAS-associated C-terminal) domain; Contains 1 PAS (PER-ARNT-SIM) domain; Contains 1 response regulatory domain; KEGG: vch:VC2369 two-component system, OmpR family, aerobic respiration control sensor histidine kinase ArcB.
 
 
 0.925
ANS84383.1
Serves as a specificity factor required for RNase E- mediated decay of the small global regulatory RNAs CsrB and CsrC, it is probably not a nuclease. Nor does its activity involve c-di- GMP, despite its domain composition. Positively modulates motility gene expression, is also required for curli expression; Contains 1 EAL domain; Contains 1 GGDEF domain.
 
  
 0.887
ANS87084.1
Putative signaling protein; Contains 1 EAL domain; Contains 1 GGDEF domain; Contains 1 MHYT domain; KEGG: vfi:VF_A0057 null; Phosphotransferases with a nitrogenous group as acceptor.
 
 
 0.882
ANS85168.1
Diguanylate cyclase; Contains 1 EAL domain; Contains 1 GGDEF domain; Contains 1 MHYT domain; KEGG: wol:WD0221 two-component system, cell cycle response regulator.
 
 
 0.881
ANS85630.1
Diguanylate cyclase DosC; Globin-coupled heme-based oxygen sensor protein displaying diguanylate cyclase (DGC) activity in response to oxygen availability. Thus, catalyzes the synthesis of cyclic diguanylate (c-di-GMP) via the condensation of 2 GTP molecules. Cyclic-di-GMP is a second messenger which controls cell surface- associated traits in bacteria (By similarity); Contains 1 GGDEF domain.
 
 
0.879
Your Current Organism:
Vibrio scophthalmi
NCBI taxonomy Id: 45658
Other names: CAIM 75, CECT 4638, CIP 105211, LMG 19158, LMG:19158, V. scophthalmi, strain A089
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.