STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
ANS85480.1Putative methyl-accepting chemotaxis protein YoaH; Contains 1 HAMP domain; Contains 1 methyl-accepting transducer domain. (629 aa)    
Predicted Functional Partners:
cheA
Histidine kinase; Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylate; it can transfer its phosphate group to either CheB or CheY (By similarity); Contains 1 cheW-like domain; Contains 1 histidine kinase domain; Contains 1 HPt domain; KEGG: vch:VC2063 two-component system, chemotaxis family, sensor kinase CheA.
 
 0.979
ANS85027.1
Hypothetical protein.
 
 0.962
ANS87308.1
Chemotaxis protein CheV; Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. Chemotaxis involves both a phosphorylation-dependent excitation and a methylation-dependent adaptation. CheV and CheW are involved in the coupling of the methyl-accepting chemoreceptors to the central two-component kinase Che; they are both necessary for efficient chemotaxis. Moreover, CheA-dependent phosphorylation of CheV is required for adaptation to attractants during B. subtilis chemotaxis; Contains 1 cheW-like domain; Contains 1 response regulatory domain.
 
 0.961
ANS84758.1
Chemotaxis protein CheV; Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. Chemotaxis involves both a phosphorylation-dependent excitation and a methylation-dependent adaptation. CheV and CheW are involved in the coupling of the methyl-accepting chemoreceptors to the central two-component kinase Che; they are both necessary for efficient chemotaxis. Moreover, CheA-dependent phosphorylation of CheV is required for adaptation to attractants during B. subtilis chemotaxis; Contains 1 cheW-like domain; Contains 1 response regulatory domain.
 
 0.956
ANS86008.1
Chemotaxis protein CheW; Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors; Contains 1 cheW-like domain.
 
 0.956
cheR
Protein-glutamate O-methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP; Contains 1 cheR-type methyltransferase domain; KEGG: vch:VC2201 chemotaxis protein methyltransferase CheR.
 
 0.940
cheB
Protein-glutamate methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 0.936
ANS86009.1
Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily; Contains 1 tr-type G (guanine nucleotide-binding) domain.
   
  0.808
ANS86014.1
Chemotaxis protein; Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. In its active (phosphorylated or acetylated) form, CheY exhibits enhanced binding to a switch component, FliM, at the flagellar motor which induces a change from counterclockwise to clockwise flagellar rotation (By similarity); Contains 1 response regulatory domain.
 
 0.795
ANS85362.1
Hypothetical protein.
   
  0.670
Your Current Organism:
Vibrio scophthalmi
NCBI taxonomy Id: 45658
Other names: CAIM 75, CECT 4638, CIP 105211, LMG 19158, LMG:19158, V. scophthalmi, strain A089
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