STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
galAAlpha-galactosidase; KEGG: vha:VIBHAR_01858 alpha-galactosidase. (579 aa)    
Predicted Functional Partners:
malZ
Alpha-glucosidase; Belongs to the glycosyl hydrolase 13 family; KEGG: kvd:KR75_26480 alpha-glucosidase.
  
 
 0.917
sacA
Beta-fructofuranosidase; Enables the bacterium to metabolize sucrose as a sole carbon source. Belongs to the glycosyl hydrolase 32 family; KEGG: vag:N646_3835 beta-fructofuranosidase.
    
 0.915
melA
Alpha-galactosidase; Belongs to the glycosyl hydrolase 4 family; KEGG: esc:Entcl_3271 alpha-galactosidase.
    
 0.905
ANS83885.1
Hypothetical protein.
  
     0.719
ANS84519.1
Outer membrane protein; Forms pores that allow passive diffusion of small molecules across the outer membrane; Belongs to the Gram-negative porin family.
  
     0.661
ANS86729.1
Cyclic di-GMP binding protein; May act as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (Potential). Binds bis-(3'-5') cyclic diguanylic acid (c- di-GMP) with a dissociation constant of 170 nM in the presence of 10 mM KCl and with 100 nM in its absence. Binds 1 to 2 c-di-GMP per subunit. Only 1 c-di-GMP is seen in the wild-type crystal, while 2 are seen in the mutant. Depending on the concentration of K(+) stoichiometries of 1:1, 1. 43:1 and 2:1 are deter [...]
  
     0.661
ANS87995.1
Hypothetical protein.
  
     0.658
ANS86097.1
Hypothetical protein.
  
     0.624
ANS85304.1
KEGG: ana:all3691 protein kinase.
  
     0.614
ruvC
Crossover junction endodeoxyribonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
       0.612
Your Current Organism:
Vibrio scophthalmi
NCBI taxonomy Id: 45658
Other names: CAIM 75, CECT 4638, CIP 105211, LMG 19158, LMG:19158, V. scophthalmi, strain A089
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