STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ANS86001.1Cytochrome c-type bioproteinis protein CcmF; Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase. Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family. (652 aa)    
Predicted Functional Partners:
ANS86000.1
Thiol:disulfide interchange protein DsbE; Involved in disulfide bond formation. Catalyzes a late, reductive step in the assembly of periplasmic c-type cytochromes, probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme. Possible subunit of a heme lyase (By similarity); Belongs to the thioredoxin family. DsbE subfamily; Contains 1 thioredoxin domain.
 
  
 0.979
ANS85998.1
Putative cytochrome c-type bioproteinis protein CcmH; May be required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase (By similarity); Belongs to the CcmH/CycL/Ccl2/NrfF family; Contains 2 TPR repeats.
 
 
 0.977
ccmE
Cytochrome c-type bioproteinis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.
 
 
 0.971
ANS85999.1
Cytochrome c-type bioproteinis protein CcmH; Possible subunit of a heme lyase.
 
  
 0.970
ccmC
Heme exporter protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.
 
  
 0.959
ANS86080.1
Thiol:disulfide interchange protein; Involved in disulfide bond formation. Catalyzes a late, reductive step in the assembly of periplasmic c-type cytochromes, probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme. Possible subunit of a heme lyase (By similarity); Belongs to the thioredoxin family. DsbE subfamily; Contains 1 thioredoxin domain.
 
  
 0.912
ANS86005.1
Heme exporter protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.
 
  
 0.910
ccmA
Cytochrome c bioproteinis ATP-binding export protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
 
   
 0.901
ANS86079.1
Formate-dependent nitrite reductase complex bifunctional subunit NrfFG; Possible subunit of a heme lyase.
  
 0.876
ANS86003.1
Heme exporter protein D; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family.
  
  
 0.858
Your Current Organism:
Vibrio scophthalmi
NCBI taxonomy Id: 45658
Other names: CAIM 75, CECT 4638, CIP 105211, LMG 19158, LMG:19158, V. scophthalmi, strain A089
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