STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANS86225.1Putative transporter; Could be a drug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2. A. 6) family. (1045 aa)    
Predicted Functional Partners:
ANS86226.1
Macrolide export protein; Part of the tripartite efflux system MacAB-TolC. MacA stimulates the ATPase activity of MacB by promoting the closed ATP-bound state of MacB, increases the capacity of MacB to bind macrolides such as erythromycin, and provides a physical link between MacB and TolC. When overexpressed, the system confers resistance against macrolides composed of 14- and 15-membered lactones but no or weak resistance against 16-membered ones. In addition, MacA binds tightly rough-core lipopolysaccharide (R- LPS), suggesting that the system could also transport R-LPS or a similar [...]
 
 
 0.971
ANS83946.1
Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family.
 
 0.863
ANS87502.1
Efflux pump periplasmic linker BepF; May contribute to resistance to some drugs, such as deoxycholate, sodium dodecyl sulfate and nalidixic acid, in the absence of BepD and BepE; Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family.
 
 0.829
ANS85806.1
Multidrug resistance protein MdtA; Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family.
 
 
 0.790
ANS85093.1
UPF0194 membrane protein YbhG; Belongs to the UPF0194 family; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.786
ANS85807.1
Probable periplasmic linker protein component of the SepABC efflux pump with unknown specificity. Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family.
 
 
 0.762
ANS85251.1
The periplasmic linker protein component of an antibiotic efflux pump. Confers resistance to numerous structurally unrelated antibiotics such as carbenicillin, chloramphenicol, erythromycin, novobiocin, streptomycin and tetracycline. Is not involved in organic solvent efflux. Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family.
 
 
 0.750
ANS86836.1
Cell membrane lipoprotein, involved in cell membrane permeability to hydrophobic compounds such as antibiotics, dyes and detergents. Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family.
 
 0.672
ANS84513.1
Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family.
 
 
 0.653
ANS85328.1
Putative membrane fusion protein SilB; Component of the sil cation efflux system that confers resistance to silver. May be part of a three-component cation/proton antiporter. Belongs to the membrane fusion protein (MFP) (TC 8. A. 1) family.
 
 
 0.617
Your Current Organism:
Vibrio scophthalmi
NCBI taxonomy Id: 45658
Other names: CAIM 75, CECT 4638, CIP 105211, LMG 19158, LMG:19158, V. scophthalmi, strain A089
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