STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dapD2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (343 aa)    
Predicted Functional Partners:
dapB
4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
  
 
 0.958
argD
Acetylornithine transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily; KEGG: vtu:IX91_01070 acetylornithine/N-succinyldiaminopimelate aminotransferase.
    
 0.921
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
   
  
 0.808
ANS87245.1
Hypothetical protein.
 
     0.618
birA
Biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
  
 0.592
pheT
Phenylalanine--tRNA ligase; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily; Contains 1 B5 domain; Contains 1 FDX-ACB domain; Contains 1 tRNA-binding domain; KEGG: eco:b1713 phenylalanyl-tRNA synthetase beta chain.
   
  
 0.586
metL
Aspartate kinase; In the N-terminal sectio; belongs to the aspartokinase family; In the C-terminal sectio; belongs to the homoserine dehydrogenase family; KEGG: vpa:VP2764 bifunctional aspartokinase / homoserine dehydrogenase 2.
  
  
 0.529
thrA
Aspartate kinase; In the N-terminal sectio; belongs to the aspartokinase family; In the C-terminal sectio; belongs to the homoserine dehydrogenase family; Contains 2 ACT domains; KEGG: eco:b0002 bifunctional aspartokinase / homoserine dehydrogenase 1.
  
  
 0.529
ANS84269.1
Hypothetical protein.
     
  0.499
sarS
Serine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
  
  
 0.491
Your Current Organism:
Vibrio scophthalmi
NCBI taxonomy Id: 45658
Other names: CAIM 75, CECT 4638, CIP 105211, LMG 19158, LMG:19158, V. scophthalmi, strain A089
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