STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ygiFTriphosphatase; Involved in the hydrolysis of the beta-gamma- phosphoanhydride linkage of triphosphate-containing substrates (inorganic or nucleoside-linked). Catalyzes the hydrolysis of inorganic triphosphate (PPPi), which could be cytotoxic because of its high affinity for calcium ion, thereby interfering with calcium signaling. It also hydrolyzes slowly thiamine triphosphate (ThTP). YgiF is a specific PPPase, but it contributes only marginally to the total PPPase activity in E. coli, where the main enzyme responsible for hydrolysis of PPPi is inorganic pyrophosphatase (PPase); Conta [...] (505 aa)    
Predicted Functional Partners:
ANS85103.1
UPF0208 membrane protein; Belongs to the UPF0208 family.
  
     0.608
yihI
Der GTPase-activating protein YihI; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family.
  
   
 0.561
bamC
Outer membrane protein assembly factor BamC; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
     0.558
ANS83952.1
Uncharacterized protein; Membrane; Transmembrane; Transmembrane helix.
  
     0.548
ANS86389.1
Belongs to the UPF0111 family.
       0.525
ANS84876.1
Nucleoid-associated protein; Belongs to the YejK family.
  
   
 0.500
ANS86119.1
Hypothetical protein.
  
     0.480
lptC
Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family.
  
     0.457
proQ
RNA chaperone ProQ; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities; Belongs to the ProQ family.
  
     0.457
ANS85458.1
Universal stress protein; Required for resistance to DNA-damaging agents; Belongs to the universal stress protein A family.
  
     0.449
Your Current Organism:
Vibrio scophthalmi
NCBI taxonomy Id: 45658
Other names: CAIM 75, CECT 4638, CIP 105211, LMG 19158, LMG:19158, V. scophthalmi, strain A089
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.