STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANS87084.1Putative signaling protein; Contains 1 EAL domain; Contains 1 GGDEF domain; Contains 1 MHYT domain; KEGG: vfi:VF_A0057 null; Phosphotransferases with a nitrogenous group as acceptor. (647 aa)    
Predicted Functional Partners:
ANS85630.1
Diguanylate cyclase DosC; Globin-coupled heme-based oxygen sensor protein displaying diguanylate cyclase (DGC) activity in response to oxygen availability. Thus, catalyzes the synthesis of cyclic diguanylate (c-di-GMP) via the condensation of 2 GTP molecules. Cyclic-di-GMP is a second messenger which controls cell surface- associated traits in bacteria (By similarity); Contains 1 GGDEF domain.
 
 0.899
vieA
Cyclic-guanylate-specific phosphodiesterase; Photoreceptor which exists in two forms that are reversibly interconvertible by light: the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. Belongs to the phytochrome family; Contains 1 EAL domain; Contains 2 GAF domains; Contains 2 GGDEF domains; KEGG: vch:VC1652 c-di-GMP phosphodiesterase.
 
 
 0.882
ANS87682.1
Cyclic-guanylate-specific phosphodiesterase; Contains 1 EAL domain; Contains 1 GGDEF domain; Contains 2 PAC (PAS-associated C-terminal) domains; Contains 2 PAS (PER-ARNT-SIM) domains; KEGG: bvi:Bcep1808_4032 cyclic di-GMP phosphodiesterase Gmr.
 
 
 0.874
ANS87974.1
Protein-glutamate O-methyltransferase; Plays an essential role in the maintenance and the formation of the three-dimensional structure of the biofilms at the later stages of their development. Absence of mbaA promotes the accumulation of larger amount of biomass on the surfaces at later stage of development, results in the overproduction of an extracellular polymeric substance that accumulates in the matrix of biofilms. This yields biofilms lacking the typical structure consisting of pillars of cells separated by fluid filled channels; Contains 1 EAL domain; Contains 1 GGDEF domain; Co [...]
   0.871
ANS85605.1
Cyclic di-GMP phosphodiesterase PdeB; Affects motility and biofilm formation, and is linked to the regulation of sulfate uptake and assimilation; Contains 1 EAL domain; Contains 1 GGDEF domain; Contains 1 PAS (PER-ARNT-SIM) domain.
 
 
 0.854
ANS87656.1
Cyclic-guanylate-specific phosphodiesterase; Overexpression reduces biofilm formation. Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria; Contains 1 EAL domain; KEGG: spe:Spro_4742 cyclic di-GMP phosphodiesterase Gmr.
 
  
 0.850
ANS84383.1
Serves as a specificity factor required for RNase E- mediated decay of the small global regulatory RNAs CsrB and CsrC, it is probably not a nuclease. Nor does its activity involve c-di- GMP, despite its domain composition. Positively modulates motility gene expression, is also required for curli expression; Contains 1 EAL domain; Contains 1 GGDEF domain.
 
  
 0.829
ANS87474.1
Putative signaling protein; Contains 1 EAL domain; Contains 1 GGDEF domain; Contains 1 MHYT domain; Contains 1 PAS (PER-ARNT-SIM) domain; KEGG: mbu:Mbur_0768 null; Phosphotransferases with a nitrogenous group as acceptor.
 
  
 0.828
ANS87916.1
Phytochrome-like protein cph2; Photoreceptor which exists in two forms that are reversibly interconvertible by light: the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region. Belongs to the phytochrome family; Contains 1 EAL domain; Contains 2 GAF domains; Contains 2 GGDEF domains.
  
 0.828
ANS85777.1
N,N'-diacetylchitobiose permease IIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in N,N'-diacetylchitobiose transport; Contains 1 PTS EIIC type-3 domain.
 
  
 0.818
Your Current Organism:
Vibrio scophthalmi
NCBI taxonomy Id: 45658
Other names: CAIM 75, CECT 4638, CIP 105211, LMG 19158, LMG:19158, V. scophthalmi, strain A089
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.