STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ppnPUPF0345 protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. (92 aa)    
Predicted Functional Partners:
deoA
Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
     
 0.910
ANS84842.1
Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family.
     
 0.909
ANS88018.1
Uridine phosphorylase; Cleavage of guanosine or inosine to respective bases and sugar-1-phosphate molecules. Cleaves inosine, guanosine, and adenosine with a better efficiency than MTA; Belongs to the PNP/UDP phosphorylase family; KEGG: vpa:VPA1079 uridine phosphorylase.
     
 0.909
add
Belongs to the adenosine and AMP deaminases family. Adenosine deaminase subfamily; KEGG: pge:LG71_15775 adenosine deaminase.
     
 0.901
cpdB
2',3'-cyclic-nucleotide 2'-phosphodiesterase; This bifunctional enzyme catalyzes two consecutive reactions during ribonucleic acid degradation. Converts a 2',3'- cyclic nucleotide to a 3'-nucleotide and then the 3'-nucleotide to the corresponding nucleoside and phosphate; Belongs to the 5'-nucleotidase family; KEGG: vvu:VV1_0728 2',3'-cyclic-nucleotide 2'-phosphodiesterase.
     
  0.900
hprT
Hypoxanthine phosphoribosyltransferase; Acts preferentially on hypoxanthin; has very low activity towards guanine. Inactive towards xanthine (By similarity); Belongs to the purine/pyrimidine phosphoribosyltransferase family; KEGG: ype:YPO3408 hypoxanthine phosphoribosyltransferase.
     
  0.900
gpt
Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
     
  0.900
ushA
5'-nucleotidase; Degradation of extracellular 5'-nucleotides for nutritional needs. Belongs to the 5'-nucleotidase family; KEGG: vvu:VV1_0248 5'-nucleotidase / UDP-sugar diphosphatase.
     
  0.900
udk
Belongs to the uridine kinase family; KEGG: vch:VC1038 uridine kinase.
     
  0.900
yfbR
5'-deoxynucleotidase; Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates.
     
  0.900
Your Current Organism:
Vibrio scophthalmi
NCBI taxonomy Id: 45658
Other names: CAIM 75, CECT 4638, CIP 105211, LMG 19158, LMG:19158, V. scophthalmi, strain A089
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