| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ANS84263.1 | pcbD | VSVS12_00446 | VSVS12_03582 | Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. | Belongs to the pterin-4-alpha-carbinolamine dehydratase family; KEGG: vch:VCA0827 4a-hydroxytetrahydrobiopterin dehydratase. | 0.417 |
| ANS87292.1 | pcbD | VSVS12_03583 | VSVS12_03582 | Hypothetical protein. | Belongs to the pterin-4-alpha-carbinolamine dehydratase family; KEGG: vch:VCA0827 4a-hydroxytetrahydrobiopterin dehydratase. | 0.474 |
| ANS87292.1 | phhA | VSVS12_03583 | VSVS12_03581 | Hypothetical protein. | Phenylalanine 4-monooxygenase; Belongs to the biopterin-dependent aromatic amino acid hydroxylase family; KEGG: vha:VIBHAR_05421 phenylalanine-4-hydroxylase. | 0.474 |
| ANS87532.1 | aspC | VSVS12_03832 | VSVS12_01914 | Aspartate transaminase; Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids (By similarity); Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family; KEGG: vfu:vfu_B00279 aspartate aminotransferase. | Aspartate transaminase; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family; KEGG: ype:YPO1410 aspartate aminotransferase. | 0.907 |
| ANS87532.1 | hppD | VSVS12_03832 | VSVS12_01565 | Aspartate transaminase; Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids (By similarity); Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family; KEGG: vfu:vfu_B00279 aspartate aminotransferase. | 4-hydroxyphenylpyruvate dioxygenase; Belongs to the 4HPPD family; KEGG: ppr:PBPRB1180 4-hydroxyphenylpyruvate dioxygenase. | 0.946 |
| ANS87532.1 | pcbD | VSVS12_03832 | VSVS12_03582 | Aspartate transaminase; Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids (By similarity); Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family; KEGG: vfu:vfu_B00279 aspartate aminotransferase. | Belongs to the pterin-4-alpha-carbinolamine dehydratase family; KEGG: vch:VCA0827 4a-hydroxytetrahydrobiopterin dehydratase. | 0.487 |
| ANS87532.1 | phhA | VSVS12_03832 | VSVS12_03581 | Aspartate transaminase; Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids (By similarity); Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family; KEGG: vfu:vfu_B00279 aspartate aminotransferase. | Phenylalanine 4-monooxygenase; Belongs to the biopterin-dependent aromatic amino acid hydroxylase family; KEGG: vha:VIBHAR_05421 phenylalanine-4-hydroxylase. | 0.937 |
| ANS87962.1 | pcbD | VSVS12_04263 | VSVS12_03582 | Hypothetical protein. | Belongs to the pterin-4-alpha-carbinolamine dehydratase family; KEGG: vch:VCA0827 4a-hydroxytetrahydrobiopterin dehydratase. | 0.400 |
| aacS | pcbD | VSVS12_03580 | VSVS12_03582 | Acetoacetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family; KEGG: vpa:VPA1158 acetoacetyl-CoA synthetase. | Belongs to the pterin-4-alpha-carbinolamine dehydratase family; KEGG: vch:VCA0827 4a-hydroxytetrahydrobiopterin dehydratase. | 0.420 |
| aacS | phhA | VSVS12_03580 | VSVS12_03581 | Acetoacetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family; KEGG: vpa:VPA1158 acetoacetyl-CoA synthetase. | Phenylalanine 4-monooxygenase; Belongs to the biopterin-dependent aromatic amino acid hydroxylase family; KEGG: vha:VIBHAR_05421 phenylalanine-4-hydroxylase. | 0.425 |
| aspC | ANS87532.1 | VSVS12_01914 | VSVS12_03832 | Aspartate transaminase; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family; KEGG: ype:YPO1410 aspartate aminotransferase. | Aspartate transaminase; Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids (By similarity); Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family; KEGG: vfu:vfu_B00279 aspartate aminotransferase. | 0.907 |
| aspC | hppD | VSVS12_01914 | VSVS12_01565 | Aspartate transaminase; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family; KEGG: ype:YPO1410 aspartate aminotransferase. | 4-hydroxyphenylpyruvate dioxygenase; Belongs to the 4HPPD family; KEGG: ppr:PBPRB1180 4-hydroxyphenylpyruvate dioxygenase. | 0.946 |
| aspC | pcbD | VSVS12_01914 | VSVS12_03582 | Aspartate transaminase; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family; KEGG: ype:YPO1410 aspartate aminotransferase. | Belongs to the pterin-4-alpha-carbinolamine dehydratase family; KEGG: vch:VCA0827 4a-hydroxytetrahydrobiopterin dehydratase. | 0.487 |
| aspC | phhA | VSVS12_01914 | VSVS12_03581 | Aspartate transaminase; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family; KEGG: ype:YPO1410 aspartate aminotransferase. | Phenylalanine 4-monooxygenase; Belongs to the biopterin-dependent aromatic amino acid hydroxylase family; KEGG: vha:VIBHAR_05421 phenylalanine-4-hydroxylase. | 0.937 |
| hmgA | hppD | VSVS12_01566 | VSVS12_01565 | Belongs to the homogentisate dioxygenase family; KEGG: vch:VC1345 homogentisate 1,2-dioxygenase. | 4-hydroxyphenylpyruvate dioxygenase; Belongs to the 4HPPD family; KEGG: ppr:PBPRB1180 4-hydroxyphenylpyruvate dioxygenase. | 0.999 |
| hmgA | pcbD | VSVS12_01566 | VSVS12_03582 | Belongs to the homogentisate dioxygenase family; KEGG: vch:VC1345 homogentisate 1,2-dioxygenase. | Belongs to the pterin-4-alpha-carbinolamine dehydratase family; KEGG: vch:VCA0827 4a-hydroxytetrahydrobiopterin dehydratase. | 0.618 |
| hmgA | phhA | VSVS12_01566 | VSVS12_03581 | Belongs to the homogentisate dioxygenase family; KEGG: vch:VC1345 homogentisate 1,2-dioxygenase. | Phenylalanine 4-monooxygenase; Belongs to the biopterin-dependent aromatic amino acid hydroxylase family; KEGG: vha:VIBHAR_05421 phenylalanine-4-hydroxylase. | 0.924 |
| hppD | ANS87532.1 | VSVS12_01565 | VSVS12_03832 | 4-hydroxyphenylpyruvate dioxygenase; Belongs to the 4HPPD family; KEGG: ppr:PBPRB1180 4-hydroxyphenylpyruvate dioxygenase. | Aspartate transaminase; Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids (By similarity); Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family; KEGG: vfu:vfu_B00279 aspartate aminotransferase. | 0.946 |
| hppD | aspC | VSVS12_01565 | VSVS12_01914 | 4-hydroxyphenylpyruvate dioxygenase; Belongs to the 4HPPD family; KEGG: ppr:PBPRB1180 4-hydroxyphenylpyruvate dioxygenase. | Aspartate transaminase; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family; KEGG: ype:YPO1410 aspartate aminotransferase. | 0.946 |
| hppD | hmgA | VSVS12_01565 | VSVS12_01566 | 4-hydroxyphenylpyruvate dioxygenase; Belongs to the 4HPPD family; KEGG: ppr:PBPRB1180 4-hydroxyphenylpyruvate dioxygenase. | Belongs to the homogentisate dioxygenase family; KEGG: vch:VC1345 homogentisate 1,2-dioxygenase. | 0.999 |