STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fruB-2The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in mannose transport. Contains 1 PTS EIIA type-2 domain; Contains 1 PTS EIIB type-2 domain; Contains 1 PTS EIIC type-2 domain; KEGG: lmt:LMRG_00048 PTS system, fructose-specific IIA component; overlaps another CDS with the same product name. (416 aa)    
Predicted Functional Partners:
mngA
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in fructose transport. Contains 2 PTS EIIB type-2 domains; Contains 1 PTS EIIC type-2 domain; KEGG: vch:VC1821 PTS system, fructose-specific IIB-like component; overlaps another CDS with the same product name.
  
 0.998
fruK
1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family; KEGG: vpa:VPA0812 1-phosphofructokinase.
 
  
 0.989
mtlA
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in mannitol transport (By similarity); Contains 1 PTS EIIA type-2 domain; KEGG: yfr:AW19_3321 PTS system, mannitol-specific IIA component.
 
  
 0.988
ANS87834.1
Protein-N(pi)-phosphohistidine--sugar phosphotransferase; KEGG: vch:VC1824 PTS system, nitrogen regulatory IIA component.
 
  
 0.948
ptsI
Phosphoenolpyruvate--protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
  
 0.921
ANS87833.1
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in fructose transport. Contains 2 PTS EIIB type-2 domains; Contains 1 PTS EIIC type-2 domain; KEGG: eco:b3950 PTS system, fructose-specific IIB-like component.
  
 0.908
fruA
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in fructose transport (By similarity); Contains 1 PTS EIIA type-2 domain; Contains 1 PTS EIIB type-2 domain; Contains 1 PTS EIIC type-2 domain; KEGG: vvy:VVA1395 PTS system, fructose-specific IIB component.
 
  
0.846
fruB
Involved in thermoinduction of ompC. The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane; Contains 1 PTS EIIA type-2 domain; Contains 1 PTS EIIB type-2 domain; Contains 1 PTS EIIC type-2 domain; KEGG: vvy:VVA1392 PTS system, fructose-specific IIA component.
  
0.840
ANS84719.1
HPr-like protein Crh; Involved in carbon catabolite repression (CCR); Belongs to the HPr family; Contains 1 HPr domain.
 
  
 0.806
murP
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in N-acetylmuramic acid (MurNAc) transport, yielding cytoplasmic MurNAc-6-P. Is also able to take up anhydro-N-acetylmuramic acid (anhMurNAc), but cannot phosphorylate the carbon 6, probably because of the 1,6-anhydro ring (By similarity); Contains 1 PTS EIIB type-1 domain; Contains 1 PTS EIIC type-1 domain; KEGG: vp [...]
  
  
 0.794
Your Current Organism:
Vibrio scophthalmi
NCBI taxonomy Id: 45658
Other names: CAIM 75, CECT 4638, CIP 105211, LMG 19158, LMG:19158, V. scophthalmi, strain A089
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