STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
manA-2Mannose-6-phosphate isomerase; Involved in the conversion of glucose to GDP-L-fucose, which can be converted to L-fucose, a capsular polysaccharide. Belongs to the mannose-6-phosphate isomerase type 1 family; KEGG: vcf:IR04_14310 mannose-6-phosphate isomerase. (400 aa)    
Predicted Functional Partners:
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family; KEGG: eci:UTI89_C4593 glucose-6-phosphate isomerase.
 
 
 0.933
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
    
 0.911
ANS87930.1
Phosphomannomutase; Glucose 1,6-bisphosphate synthase using 1,3- bisphosphoglycerate as a phosphate donor and a series of 1- phosphate sugars as acceptors, including glucose 1-phosphate, mannose 1-phosphate, ribose 1-phosphate and deoxyribose 1- phosphate. 5 or 6-phosphosugars are bad substrates, with the exception of glucose 6-phosphate. Also synthesizes ribose 1,5- bisphosphate. Has only low phosphopentomutase and phosphoglucomutase activities; Belongs to the phosphohexose mutase family; KEGG: vfu:vfu_B01099 phosphomannomutase.
  
 
 0.911
glmS
Glutamine--fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
     
 0.910
nagB
Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
     
 0.910
manA
Mannose-6-phosphate isomerase; Involved in the conversion of glucose to GDP-L-fucose, which can be converted to L-fucose, a capsular polysaccharide. Belongs to the mannose-6-phosphate isomerase type 1 family; KEGG: vvy:VVA1390 mannose-6-phosphate isomerase.
  
  
 
0.905
fbp
Fructose-bisphosphatase; Belongs to the FBPase class 1 family; KEGG: vvu:VV1_0707 fructose-1,6-bisphosphatase I.
     
 0.904
scrK
Fructokinase; Belongs to the carbohydrate kinase PfkB family; KEGG: vag:N646_3834 fructokinase.
    
 0.904
glpX
Fructose-bisphosphatase; Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate; Belongs to the FBPase class 2 family; KEGG: vch:VC2688 fructose-1,6-bisphosphatase II.
     
 0.900
ANS87838.1
The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; Contains 1 PTS EIIC type-2 domain; KEGG: vpa:VPA0297 PTS system, fructose-specific IIB-like component.
  
  
 0.664
Your Current Organism:
Vibrio scophthalmi
NCBI taxonomy Id: 45658
Other names: CAIM 75, CECT 4638, CIP 105211, LMG 19158, LMG:19158, V. scophthalmi, strain A089
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.