STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proC-2Hypothetical protein; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (262 aa)    
Predicted Functional Partners:
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
  
  
 
0.887
KIH69979.1
Proline dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.879
rocA
Catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. RocA subfamily.
   
 
  0.836
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 0.820
KIH70678.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.789
KIH70804.1
Proline racemase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the proline racemase family.
     
 0.771
KIH69783.1
Proline racemase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the proline racemase family.
     
 0.771
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
 
 
 0.729
KIH71301.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.531
KIH70584.1
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.508
Your Current Organism:
Salinicoccus roseus
NCBI taxonomy Id: 45670
Other names: ATCC 49258, CCM 3516, CCUG 43291, CIP 104761, DSM 5351, JCM 14630, Micrococcus sp. CCM 168, S. roseus
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