Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KIH70653.1Major facilitator transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (463 aa)    
Predicted Functional Partners:
xylA
Xylose isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the xylose isomerase family.
 
   
 0.773
xylB
Xylulose kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.709
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
  0.564
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
     
 0.564
tdk
Thymidine kinase; Catalyzes the formation of thymidine 5'-phosphate from thymidine; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.564
KIH71668.1
Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
  0.486
gpmI
Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
    
  0.482
KIH71160.1
Uridylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.477
KIH71667.1
Ribonucleotide-diphosphate reductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.456
KIH71626.1
Glyceraldehyde-3-phosphate dehydrogenase; NAD-dependent; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; active during glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
    
 0.445
Your Current Organism:
Salinicoccus roseus
NCBI taxonomy Id: 45670
Other names: ATCC 49258, CCM 3516, CCUG 43291, CIP 104761, DSM 5351, JCM 14630, Micrococcus sp. CCM 168, S. roseus
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