node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CSBG_00113 | CSBG_00114 | CSBG_00113 | CSBG_00114 | Acetolactate synthase, small subunit. | 2-isopropylmalate synthase/homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.990 |
CSBG_00113 | CSBG_00119 | CSBG_00113 | CSBG_00119 | Acetolactate synthase, small subunit. | Acetolactate synthase, large subunit, biosynthetic type. | 0.999 |
CSBG_00113 | CSBG_00974 | CSBG_00113 | CSBG_00974 | Acetolactate synthase, small subunit. | Hypothetical protein. | 0.741 |
CSBG_00113 | CSBG_02026 | CSBG_00113 | CSBG_02026 | Acetolactate synthase, small subunit. | Hypothetical protein. | 0.709 |
CSBG_00113 | CSBG_02099 | CSBG_00113 | CSBG_02099 | Acetolactate synthase, small subunit. | Branched-chain-amino-acid aminotransferase. | 0.768 |
CSBG_00113 | CSBG_02233 | CSBG_00113 | CSBG_02233 | Acetolactate synthase, small subunit. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.927 |
CSBG_00113 | CSBG_03053 | CSBG_00113 | CSBG_03053 | Acetolactate synthase, small subunit. | Homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.967 |
CSBG_00113 | ilvC | CSBG_00113 | CSBG_00120 | Acetolactate synthase, small subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.999 |
CSBG_00113 | leuA | CSBG_00113 | CSBG_02404 | Acetolactate synthase, small subunit. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.974 |
CSBG_00113 | leuB | CSBG_00113 | CSBG_00117 | Acetolactate synthase, small subunit. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.995 |
CSBG_00114 | CSBG_00113 | CSBG_00114 | CSBG_00113 | 2-isopropylmalate synthase/homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Acetolactate synthase, small subunit. | 0.990 |
CSBG_00114 | CSBG_00119 | CSBG_00114 | CSBG_00119 | 2-isopropylmalate synthase/homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Acetolactate synthase, large subunit, biosynthetic type. | 0.970 |
CSBG_00114 | CSBG_00974 | CSBG_00114 | CSBG_00974 | 2-isopropylmalate synthase/homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Hypothetical protein. | 0.929 |
CSBG_00114 | CSBG_02026 | CSBG_00114 | CSBG_02026 | 2-isopropylmalate synthase/homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Hypothetical protein. | 0.963 |
CSBG_00114 | CSBG_02099 | CSBG_00114 | CSBG_02099 | 2-isopropylmalate synthase/homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Branched-chain-amino-acid aminotransferase. | 0.962 |
CSBG_00114 | CSBG_02233 | CSBG_00114 | CSBG_02233 | 2-isopropylmalate synthase/homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.943 |
CSBG_00114 | CSBG_03053 | CSBG_00114 | CSBG_03053 | 2-isopropylmalate synthase/homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.918 |
CSBG_00114 | ilvC | CSBG_00114 | CSBG_00120 | 2-isopropylmalate synthase/homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.883 |
CSBG_00114 | leuA | CSBG_00114 | CSBG_02404 | 2-isopropylmalate synthase/homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.890 |
CSBG_00114 | leuB | CSBG_00114 | CSBG_00117 | 2-isopropylmalate synthase/homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.971 |