| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| era | recO | CSBG_02441 | CSBG_02440 | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.949 |
| era | rpsF | CSBG_02441 | CSBG_03290 | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. | 0.934 |
| era | rpsG | CSBG_02441 | CSBG_00042 | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.939 |
| era | rpsI | CSBG_02441 | CSBG_00082 | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. | 0.910 |
| era | rpsJ | CSBG_02441 | CSBG_00045 | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.891 |
| era | rpsL | CSBG_02441 | CSBG_00041 | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. | 0.888 |
| era | rpsO | CSBG_02441 | CSBG_01755 | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. | 0.890 |
| era | rpsP | CSBG_02441 | CSBG_01788 | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. | 0.914 |
| era | rpsZ | CSBG_02441 | CSBG_00059 | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 30S ribosomal protein S14 type Z; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site. | 0.885 |
| era | ybeY | CSBG_02441 | CSBG_02443 | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Metalloprotein, YbeY/UPF0054family; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.994 |
| recO | era | CSBG_02440 | CSBG_02441 | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.949 |
| recO | ybeY | CSBG_02440 | CSBG_02443 | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | Metalloprotein, YbeY/UPF0054family; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.690 |
| rpsF | era | CSBG_03290 | CSBG_02441 | 30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.934 |
| rpsF | rpsG | CSBG_03290 | CSBG_00042 | 30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. | 30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.998 |
| rpsF | rpsI | CSBG_03290 | CSBG_00082 | 30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. | 30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. | 0.998 |
| rpsF | rpsJ | CSBG_03290 | CSBG_00045 | 30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.998 |
| rpsF | rpsL | CSBG_03290 | CSBG_00041 | 30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. | 30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. | 0.998 |
| rpsF | rpsO | CSBG_03290 | CSBG_01755 | 30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. | 30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. | 0.998 |
| rpsF | rpsP | CSBG_03290 | CSBG_01788 | 30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. | 30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. | 0.998 |
| rpsF | rpsZ | CSBG_03290 | CSBG_00059 | 30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. | 30S ribosomal protein S14 type Z; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site. | 0.997 |
