STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
CSBG_02472RNA polymerase sigma-F factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (251 aa)    
Predicted Functional Partners:
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
 
 0.995
CSBG_02474
Anti-sigma F factor antagonist; Belongs to the anti-sigma-factor antagonist family.
 
  
 0.972
CSBG_02471
Stage V sporulation protein AC.
 
     0.855
CSBG_02470
Stage V sporulation protein AD.
 
     0.840
CSBG_02469
Stage V sporulation protein AE.
 
     0.831
sigA
RNA polymerase sigma factor rpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
  
 
0.807
CSBG_01316
Stage IV sporulation protein B.
  
   
 0.775
CSBG_01317
Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.769
CSBG_01829
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
     0.734
CSBG_03110
Stage II sporulation protein E.
  
   
 0.734
Your Current Organism:
Clostridium sp. 7243FAA
NCBI taxonomy Id: 457396
Other names: C. sp. 7_2_43FAA, Clostridium sp. 7_2_43FAA
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.