STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CSBG_03492sigma-E processing peptidase SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. (265 aa)    
Predicted Functional Partners:
CSBG_03110
Stage II sporulation protein E.
  
  
 0.959
CSBG_01842
RNA polymerase sigma-G factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.929
CSBG_01843
RNA polymerase sigma-E factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.923
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.847
CSBG_02463
Stage II sporulation protein P.
  
   
 0.836
CSBG_02892
Stage II sporulation protein R.
 
   
 0.828
CSBG_02445
Sporulation protein YqfD.
  
   
 0.822
CSBG_01841
YlmC/YmxH family sporulation protein.
 
   
 0.821
CSBG_01319
Stage II sporulation protein M.
  
  
 0.807
CSBG_01301
Stage III sporulation protein AE.
  
    0.772
Your Current Organism:
Clostridium sp. 7243FAA
NCBI taxonomy Id: 457396
Other names: C. sp. 7_2_43FAA, Clostridium sp. 7_2_43FAA
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.