EHL68568.1 protein (Synergistes sp. 31syn1) - STRING interaction network

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EHL68568.1

Hypothetical protein. (336 aa)

Predicted Functional Partners:

hisI

0.989

cobD

0.980

cobQ

0.969

hisB

0.956

hisD

0.953

hisH

0.952

hisF

0.941

aroK

0.916

hisA

0.894

EHL69897.1

0.892

Your Current Organism:

Synergistes sp. 31syn1

NCBI taxonomy Id: 457415
Other names: S. sp. 3_1_syn1, Synergistes sp. 3_1_syn1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EHL68568.1	EHL69897.1	HMPREF1006_02763	HMPREF1006_01853	Hypothetical protein.	ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.	0.892
EHL68568.1	aroK	HMPREF1006_02763	HMPREF1006_01668	Hypothetical protein.	Hypothetical protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.	0.916
EHL68568.1	cobD	HMPREF1006_02763	HMPREF1006_02764	Hypothetical protein.	Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.	0.980
EHL68568.1	cobQ	HMPREF1006_02763	HMPREF1006_02743	Hypothetical protein.	Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.	0.969
EHL68568.1	hisA	HMPREF1006_02763	HMPREF1006_01855	Hypothetical protein.	1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase.	0.894
EHL68568.1	hisB	HMPREF1006_02763	HMPREF1006_01854	Hypothetical protein.	Hypothetical protein.	0.956
EHL68568.1	hisD	HMPREF1006_02763	HMPREF1006_01887	Hypothetical protein.	Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.	0.953
EHL68568.1	hisF	HMPREF1006_02763	HMPREF1006_01858	Hypothetical protein.	Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.	0.941
EHL68568.1	hisH	HMPREF1006_02763	HMPREF1006_01857	Hypothetical protein.	Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.	0.952
EHL68568.1	hisI	HMPREF1006_02763	HMPREF1006_01856	Hypothetical protein.	phosphoribosyl-ATP diphosphatase; In the N-terminal section; belongs to the PRA-CH family.	0.989
EHL69897.1	EHL68568.1	HMPREF1006_01853	HMPREF1006_02763	ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.	Hypothetical protein.	0.892
EHL69897.1	aroK	HMPREF1006_01853	HMPREF1006_01668	ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.	Hypothetical protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.	0.541
EHL69897.1	hisA	HMPREF1006_01853	HMPREF1006_01855	ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.	1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase.	0.998
EHL69897.1	hisB	HMPREF1006_01853	HMPREF1006_01854	ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.	Hypothetical protein.	0.996
EHL69897.1	hisD	HMPREF1006_01853	HMPREF1006_01887	ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.	Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.	0.990
EHL69897.1	hisF	HMPREF1006_01853	HMPREF1006_01858	ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.	Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.	0.997
EHL69897.1	hisH	HMPREF1006_01853	HMPREF1006_01857	ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.	Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.	0.995
EHL69897.1	hisI	HMPREF1006_01853	HMPREF1006_01856	ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.	phosphoribosyl-ATP diphosphatase; In the N-terminal section; belongs to the PRA-CH family.	0.999
aroK	EHL68568.1	HMPREF1006_01668	HMPREF1006_02763	Hypothetical protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.	Hypothetical protein.	0.916
aroK	EHL69897.1	HMPREF1006_01668	HMPREF1006_01853	Hypothetical protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.	ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.	0.541