Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CBFG_02448Ser/Thr phosphatase family protein. (484 aa)    
Predicted Functional Partners:
CBFG_04129
5'-nucleotidase, C-terminal domain protein; Belongs to the 5'-nucleotidase family.
  
 
 0.801
guaA-2
GMP synthase (glutamine-hydrolyzing) domain protein.
 
  
 0.795
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
    
 0.767
CBFG_03620
Hypothetical protein.
    
 0.716
xpt
Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
  
 
  0.663
CBFG_03461
Putative sortase, SrtB family.
  
  
  0.606
purB
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
     
 0.589
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 
  0.582
CBFG_02851
MazG nucleotide pyrophosphohydrolase domain protein.
     
  0.574
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
  0.574
Your Current Organism:
Clostridiales bacterium 1747FAA
NCBI taxonomy Id: 457421
Other names: C. bacterium 1_7_47FAA, Clostridiales bacterium 1_7_47FAA
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