Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EFL20463.1Probable alginate lyase. (257 aa)    
Predicted Functional Partners:
EFL24877.1
Non-specific serine/threonine protein kinase.
    
 0.688
EFL20462.1
Non-specific serine/threonine protein kinase.
 
     0.674
guaA
GMP synthase (Glutamine amidotransferase); Catalyzes the synthesis of GMP from XMP.
     
  0.650
EFL22321.1
Catalase HPII.
    
  0.569
EFL27770.1
Conserved hypothetical protein.
 
 
 0.552
EFL22624.1
Alpha-1,2-mannosidase.
  
     0.535
EFL23103.1
Chitinase.
  
  
  0.534
EFL28121.1
NHL repeat containing protein.
     
  0.528
EFL20464.1
OmpA/MotB.
       0.524
vgb
Virginiamycin B lyase (Streptogramin B lyase); Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2- amino-butenoic acid.
  
  
  0.512
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
Server load: low (8%) [HD]