Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EFL20737.1Xre family toxin-antitoxin system, antitoxin component. (207 aa)    
Predicted Functional Partners:
EFL20739.1
Glutamate synthase; Belongs to the glutamate synthase family.
 
     0.951
EFL20740.1
FwdC/FmdC family protein.
 
     0.949
EFL20741.1
Glutamine amidotransferase, class-II protein.
 
     0.949
EFL20742.1
Glutamine synthetase, type III; Truncated CDS; unextendable partial coding region; Belongs to the glutamine synthetase family.
 
    0.912
EFL20738.1
Sarcosine oxidase, monomeric form.
       0.784
EFL28514.1
Putative Helix-turn-helix domain protein.
  
     0.624
EFL21160.1
cro/CI family transcriptional regulator.
  
     0.530
EFL24834.1
Transcriptional regulator, XRE family with cupin sensor.
  
  
  0.530
EFL24122.1
Ferredoxin oxidoreductase, alpha subunit.
    
  0.504
EFL23529.1
Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
     
  0.493
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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