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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFL20951.1ATP-dependent DNA helicase RecQ. (621 aa)    
Predicted Functional Partners:
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.907
EFL22753.1
RecQ family ATP-dependent DNA helicase; Truncated CDS.
  
  
 
0.894
EFL21138.1
Putative nuclease sbcCD subunit C.
  
 0.886
EFL23398.1
Putative ATP-dependent DNA helicase.
  
 0.880
EFL23399.1
Putative ATP-dependent DNA helicase (UvrD/REP).
  
 0.880
EFL26955.1
DNA polymerase I.
  
 0.871
EFL26957.1
DNA polymerase I.
  
 0.871
topA
DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...]
  
 0.850
EFL25306.1
ATP-dependent DNA helicase PcrA.
  
 0.835
EFL27482.1
Putative ATP-dependent RNA helicase; Truncated CDS.
 
 0.821
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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