Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EFL21036.1HhH-GPD family base excision DNA repair protein; Truncated CDS. (132 aa)    
Predicted Functional Partners:
EFL22410.1
Exodeoxyribonuclease III.
  
 0.751
EFL23743.1
Exodeoxyribonuclease III.
  
 0.751
EFL24586.1
Endonuclease/exonuclease/phosphatase.
  
 0.751
nfo
Apurinic endonuclease (APN1); Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.
  
 
 0.746
EFL27407.1
Probable 5'-3' exonuclease.
 
 
 
 0.666
EFL20647.1
Integral membrane protein.
 
     0.630
EFL24972.1
Conserved hypothetical protein.
  
 
 0.602
EFL26955.1
DNA polymerase I.
   
 
 0.598
EFL26957.1
DNA polymerase I.
   
 
 0.598
EFL21037.1
RNA polymerase sigma-F factor; Belongs to the sigma-70 factor family.
       0.591
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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