def-2 protein (Streptomyces himastatinicus) - STRING interaction network

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def-2

Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (185 aa)

Predicted Functional Partners:

rplT

0.938

rplV

0.904

rplI

0.902

rplU

0.899

rplQ

0.898

rpmA

0.892

rplS

0.891

rplX

0.889

rpsP

0.888

rplK

0.888

Your Current Organism:

Streptomyces himastatinicus

NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
def-2	rplI	SSOG_00773	SSOG_04419	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Ribosomal protein L9; Binds to the 23S rRNA.	0.902
def-2	rplK	SSOG_00773	SSOG_03804	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	0.888
def-2	rplQ	SSOG_00773	SSOG_03757	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Ribosomal protein L17.	0.898
def-2	rplS	SSOG_00773	SSOG_02630	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.	0.891
def-2	rplT	SSOG_00773	SSOG_01717	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.938
def-2	rplU	SSOG_00773	SSOG_05861	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.899
def-2	rplV	SSOG_00773	SSOG_03781	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.	0.904
def-2	rplX	SSOG_00773	SSOG_03775	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.	0.889
def-2	rpmA	SSOG_00773	SSOG_05862	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.	0.892
def-2	rpsP	SSOG_00773	SSOG_02634	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.	0.888
rplI	def-2	SSOG_04419	SSOG_00773	Ribosomal protein L9; Binds to the 23S rRNA.	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	0.902
rplI	rplK	SSOG_04419	SSOG_03804	Ribosomal protein L9; Binds to the 23S rRNA.	Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	0.998
rplI	rplQ	SSOG_04419	SSOG_03757	Ribosomal protein L9; Binds to the 23S rRNA.	Ribosomal protein L17.	0.999
rplI	rplS	SSOG_04419	SSOG_02630	Ribosomal protein L9; Binds to the 23S rRNA.	Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.	0.999
rplI	rplT	SSOG_04419	SSOG_01717	Ribosomal protein L9; Binds to the 23S rRNA.	Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.999
rplI	rplU	SSOG_04419	SSOG_05861	Ribosomal protein L9; Binds to the 23S rRNA.	Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.999
rplI	rplV	SSOG_04419	SSOG_03781	Ribosomal protein L9; Binds to the 23S rRNA.	Ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.	0.999
rplI	rplX	SSOG_04419	SSOG_03775	Ribosomal protein L9; Binds to the 23S rRNA.	Ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.	0.999
rplI	rpmA	SSOG_04419	SSOG_05862	Ribosomal protein L9; Binds to the 23S rRNA.	Ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.	0.999
rplI	rpsP	SSOG_04419	SSOG_02634	Ribosomal protein L9; Binds to the 23S rRNA.	Ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.	0.999

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