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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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sbcDPutative nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. (386 aa)    
Predicted Functional Partners:
EFL21138.1
Putative nuclease sbcCD subunit C.
 
 0.999
EFL26955.1
DNA polymerase I.
  
 0.931
EFL26957.1
DNA polymerase I.
  
 0.931
EFL23393.1
Putative ATP-dependent DNA helicase PcrA.
  
 0.927
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.872
EFL22753.1
RecQ family ATP-dependent DNA helicase; Truncated CDS.
 
 0.847
EFL22766.1
ATP-dependent helicase DinG.
   
 0.846
EFL27407.1
Probable 5'-3' exonuclease.
   
 0.817
EFL21140.1
Sulfate transporter.
  
   0.804
EFL20951.1
ATP-dependent DNA helicase RecQ.
  
 0.793
Your Current Organism:
Streptomyces himastatinicus
NCBI taxonomy Id: 457427
Other names: S. himastatinicus ATCC 53653, Streptomyces himastatinicus ATCC 53653, Streptomyces himastatinicus str. ATCC 53653, Streptomyces himastatinicus strain ATCC 53653, Streptomyces hygroscopicus ATCC 53653
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